Global Survey of the Frequency of Atrial Fibrillation-Associated Stroke: Embolic Stroke of Undetermined Source Global Registry.
Identifieur interne : 001E15 ( Main/Exploration ); précédent : 001E14; suivant : 001E16Global Survey of the Frequency of Atrial Fibrillation-Associated Stroke: Embolic Stroke of Undetermined Source Global Registry.
Auteurs : Kanjana S. Perera [Canada] ; Thomas Vanassche [Canada] ; Jackie Bosch [Canada] ; Balakumar Swaminathan [Canada] ; Hardi Mundl [Canada] ; Mohana Giruparajah [Canada] ; Miguel A. Barboza [Canada] ; Martin J. O'Donnell [Canada] ; Maia Gomez-Schneider [Canada] ; Graeme J. Hankey [Canada] ; Byung-Woo Yoon [Canada] ; Artemio Roxas [Canada] ; Philippa Lavallee [Canada] ; Joao Sargento-Freitas [Canada] ; Nikolay Shamalov [Canada] ; Raf Brouns [Canada] ; Rubens J. Gagliardi [Canada] ; Scott E. Kasner [Canada] ; Alessio Pieroni [Canada] ; Philipp Vermehren [Canada] ; Kazuo Kitagawa [Canada] ; Yongjun Wang [Canada] ; Keith Muir [Canada] ; Jonathan M. Coutinho [Canada] ; Stuart J. Connolly [Canada] ; Robert G. Hart [Canada]Source :
- Stroke [ 1524-4628 ] ; 2016.
Descripteurs français
- KwdFr :
- Accident ischémique transitoire (mortalité), Accident ischémique transitoire (épidémiologie), Accident ischémique transitoire (étiologie), Accident vasculaire cérébral (mortalité), Accident vasculaire cérébral (épidémiologie), Accident vasculaire cérébral (étiologie), Adulte d'âge moyen, Embolie intracrânienne (mortalité), Embolie intracrânienne (épidémiologie), Embolie intracrânienne (étiologie), Encéphalopathie ischémique (mortalité), Encéphalopathie ischémique (épidémiologie), Encéphalopathie ischémique (étiologie), Enregistrements, Facteurs de l'âge, Facteurs sexuels, Femelle, Fibrillation auriculaire (), Humains, Incidence, Mâle, Sujet âgé, Taux de survie, Électrocardiographie.
- MESH :
- mortalité : Accident ischémique transitoire, Accident vasculaire cérébral, Embolie intracrânienne, Encéphalopathie ischémique.
- épidémiologie : Accident ischémique transitoire, Accident vasculaire cérébral, Embolie intracrânienne, Encéphalopathie ischémique.
- étiologie : Accident ischémique transitoire, Accident vasculaire cérébral, Embolie intracrânienne, Encéphalopathie ischémique.
- Adulte d'âge moyen, Enregistrements, Facteurs de l'âge, Facteurs sexuels, Femelle, Fibrillation auriculaire, Humains, Incidence, Mâle, Sujet âgé, Taux de survie, Électrocardiographie.
English descriptors
- KwdEn :
- Age Factors, Aged, Atrial Fibrillation (complications), Brain Ischemia (epidemiology), Brain Ischemia (etiology), Brain Ischemia (mortality), Electrocardiography, Female, Humans, Incidence, Intracranial Embolism (epidemiology), Intracranial Embolism (etiology), Intracranial Embolism (mortality), Ischemic Attack, Transient (epidemiology), Ischemic Attack, Transient (etiology), Ischemic Attack, Transient (mortality), Male, Middle Aged, Registries, Sex Factors, Stroke (epidemiology), Stroke (etiology), Stroke (mortality), Survival Rate.
- MESH :
- complications : Atrial Fibrillation.
- epidemiology : Brain Ischemia, Intracranial Embolism, Ischemic Attack, Transient, Stroke.
- etiology : Brain Ischemia, Intracranial Embolism, Ischemic Attack, Transient, Stroke.
- mortality : Brain Ischemia, Intracranial Embolism, Ischemic Attack, Transient, Stroke.
- Age Factors, Aged, Electrocardiography, Female, Humans, Incidence, Male, Middle Aged, Registries, Sex Factors, Survival Rate.
Abstract
Atrial fibrillation (AF) is increasingly recognized as the single most important cause of disabling ischemic stroke in the elderly. We undertook an international survey to characterize the frequency of AF-associated stroke, methods of AF detection, and patient features.
DOI: 10.1161/STROKEAHA.116.013378
PubMed: 27507860
Affiliations:
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Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Global Survey of the Frequency of Atrial Fibrillation-Associated Stroke: Embolic Stroke of Undetermined Source Global Registry.</title><author><name sortKey="Perera, Kanjana S" sort="Perera, Kanjana S" uniqKey="Perera K" first="Kanjana S" last="Perera">Kanjana S. Perera</name><affiliation wicri:level="1"><nlm:affiliation>From the Population Health Research Institute, McMaster University, Hamilton Health Sciences, Ontario, Canada (K.S.P., J.B., B.S., M.G., S.J.C., R.G.H.); Department of Cardiovascular Sciences, University of Leuven, Belgium (T.V.); Bayer-Pharma AG, Wuppertal, Germany (H.M.); Instituto Nacional de Neurologia y Neurocirugia, Mexico D.F., Mexico (M.A.B.); University of Galway, Ireland (M.J.O.); Institute for Neurological Research, Fundacion para la Lucha contra las Enfermedades Neurologicas de la Infancia (FLENI), Buenos Aires, Argentina (M.G.-S.); School of Medicine and Pharmacology, University of Western Australia, Sir Charles Gairdner Hospital, Perth, Australia (G.J.H.); Department of Neurology, Seoul National University Hospital, Korea (B.-W.Y.); Medical City Hospital, Manila, Philippines (A.R.); Department of Neurology, Bichat Hospital, Paris, France (P.L.); Centro Hospitalar e Universitário de Coimbra, Portugal (J.S.-F.); Pirogov Russian National Research Medical University, Moscow, Russia (N.S.); Universitair Ziekenhuis Brussel, Belgium (R.B.); Santa Casa de São Paulo, Medical School, Brazil (R.J.G.); Department of Neurology, Hospital of the University of Pennsylvania, Philadelphia (S.E.K.); Emergency Department Stroke Unit, Hospital Policlinico Umberto I, Department of Neurology and Psychiatry, 'Sapienza' University, Rome, Italy (A.P.); Department of Neurology, University Hospital Heidelberg, Germany (P.V.); Department of Neurology, Tokyo Women's Medical University, Japan (K.K.); Department of Neurology, Beijing Tiantan Hospital, Capital Medical University, China (Y.W.); Institute of Neuroscience & Psychology, University of Glasgow, Queen Elizabeth University Hospital, United Kingdom (K.M.); and Academic Medical Center, Amsterdam, the Netherlands (J.M.C.). kanjana.perera@phri.ca.</nlm:affiliation><country wicri:rule="url">Canada</country></affiliation></author><author><name sortKey="Vanassche, Thomas" sort="Vanassche, Thomas" uniqKey="Vanassche T" first="Thomas" last="Vanassche">Thomas Vanassche</name><affiliation wicri:level="4"><nlm:affiliation>From the Population Health Research Institute, McMaster University, Hamilton Health Sciences, Ontario, Canada (K.S.P., J.B., B.S., M.G., S.J.C., R.G.H.); Department of Cardiovascular Sciences, University of Leuven, Belgium (T.V.); Bayer-Pharma AG, Wuppertal, Germany (H.M.); Instituto Nacional de Neurologia y Neurocirugia, Mexico D.F., Mexico (M.A.B.); University of Galway, Ireland (M.J.O.); Institute for Neurological Research, Fundacion para la Lucha contra las Enfermedades Neurologicas de la Infancia (FLENI), Buenos Aires, Argentina (M.G.-S.); School of Medicine and Pharmacology, University of Western Australia, Sir Charles Gairdner Hospital, Perth, Australia (G.J.H.); Department of Neurology, Seoul National University Hospital, Korea (B.-W.Y.); Medical City Hospital, Manila, Philippines (A.R.); Department of Neurology, Bichat Hospital, Paris, France (P.L.); Centro Hospitalar e Universitário de Coimbra, Portugal (J.S.-F.); Pirogov Russian National Research Medical University, Moscow, Russia (N.S.); Universitair Ziekenhuis Brussel, Belgium (R.B.); Santa Casa de São Paulo, Medical School, Brazil (R.J.G.); Department of Neurology, Hospital of the University of Pennsylvania, Philadelphia (S.E.K.); Emergency Department Stroke Unit, Hospital Policlinico Umberto I, Department of Neurology and Psychiatry, 'Sapienza' University, Rome, Italy (A.P.); Department of Neurology, University Hospital Heidelberg, Germany (P.V.); Department of Neurology, Tokyo Women's Medical University, Japan (K.K.); Department of Neurology, Beijing Tiantan Hospital, Capital Medical University, China (Y.W.); Institute of Neuroscience & Psychology, University of Glasgow, Queen Elizabeth University Hospital, United Kingdom (K.M.); and Academic Medical Center, Amsterdam, the Netherlands (J.M.C.).</nlm:affiliation><orgName type="university">Université McMaster</orgName><country>Canada</country><placeName><settlement type="city">Hamilton (Ontario)</settlement><region type="state">Ontario</region></placeName></affiliation></author><author><name sortKey="Bosch, Jackie" sort="Bosch, Jackie" uniqKey="Bosch J" first="Jackie" last="Bosch">Jackie Bosch</name><affiliation wicri:level="4"><nlm:affiliation>From the Population Health Research Institute, McMaster University, Hamilton Health Sciences, Ontario, Canada (K.S.P., J.B., B.S., M.G., S.J.C., R.G.H.); Department of Cardiovascular Sciences, University of Leuven, Belgium (T.V.); Bayer-Pharma AG, Wuppertal, Germany (H.M.); Instituto Nacional de Neurologia y Neurocirugia, Mexico D.F., Mexico (M.A.B.); University of Galway, Ireland (M.J.O.); Institute for Neurological Research, Fundacion para la Lucha contra las Enfermedades Neurologicas de la Infancia (FLENI), Buenos Aires, Argentina (M.G.-S.); School of Medicine and Pharmacology, University of Western Australia, Sir Charles Gairdner Hospital, Perth, Australia (G.J.H.); Department of Neurology, Seoul National University Hospital, Korea (B.-W.Y.); Medical City Hospital, Manila, Philippines (A.R.); Department of Neurology, Bichat Hospital, Paris, France (P.L.); Centro Hospitalar e Universitário de Coimbra, Portugal (J.S.-F.); Pirogov Russian National Research Medical University, Moscow, Russia (N.S.); Universitair Ziekenhuis Brussel, Belgium (R.B.); Santa Casa de São Paulo, Medical School, Brazil (R.J.G.); Department of Neurology, Hospital of the University of Pennsylvania, Philadelphia (S.E.K.); Emergency Department Stroke Unit, Hospital Policlinico Umberto I, Department of Neurology and Psychiatry, 'Sapienza' University, Rome, Italy (A.P.); Department of Neurology, University Hospital Heidelberg, Germany (P.V.); Department of Neurology, Tokyo Women's Medical University, Japan (K.K.); Department of Neurology, Beijing Tiantan Hospital, Capital Medical University, China (Y.W.); Institute of Neuroscience & Psychology, University of Glasgow, Queen Elizabeth University Hospital, United Kingdom (K.M.); and Academic Medical Center, Amsterdam, the Netherlands (J.M.C.).</nlm:affiliation><orgName type="university">Université McMaster</orgName><country>Canada</country><placeName><settlement type="city">Hamilton (Ontario)</settlement><region type="state">Ontario</region></placeName></affiliation></author><author><name sortKey="Swaminathan, Balakumar" sort="Swaminathan, Balakumar" uniqKey="Swaminathan B" first="Balakumar" last="Swaminathan">Balakumar Swaminathan</name><affiliation wicri:level="4"><nlm:affiliation>From the Population Health Research Institute, McMaster University, Hamilton Health Sciences, Ontario, Canada (K.S.P., J.B., B.S., M.G., S.J.C., R.G.H.); Department of Cardiovascular Sciences, University of Leuven, Belgium (T.V.); Bayer-Pharma AG, Wuppertal, Germany (H.M.); Instituto Nacional de Neurologia y Neurocirugia, Mexico D.F., Mexico (M.A.B.); University of Galway, Ireland (M.J.O.); Institute for Neurological Research, Fundacion para la Lucha contra las Enfermedades Neurologicas de la Infancia (FLENI), Buenos Aires, Argentina (M.G.-S.); School of Medicine and Pharmacology, University of Western Australia, Sir Charles Gairdner Hospital, Perth, Australia (G.J.H.); Department of Neurology, Seoul National University Hospital, Korea (B.-W.Y.); Medical City Hospital, Manila, Philippines (A.R.); Department of Neurology, Bichat Hospital, Paris, France (P.L.); Centro Hospitalar e Universitário de Coimbra, Portugal (J.S.-F.); Pirogov Russian National Research Medical University, Moscow, Russia (N.S.); Universitair Ziekenhuis Brussel, Belgium (R.B.); Santa Casa de São Paulo, Medical School, Brazil (R.J.G.); Department of Neurology, Hospital of the University of Pennsylvania, Philadelphia (S.E.K.); Emergency Department Stroke Unit, Hospital Policlinico Umberto I, Department of Neurology and Psychiatry, 'Sapienza' University, Rome, Italy (A.P.); Department of Neurology, University Hospital Heidelberg, Germany (P.V.); Department of Neurology, Tokyo Women's Medical University, Japan (K.K.); Department of Neurology, Beijing Tiantan Hospital, Capital Medical University, China (Y.W.); Institute of Neuroscience & Psychology, University of Glasgow, Queen Elizabeth University Hospital, United Kingdom (K.M.); and Academic Medical Center, Amsterdam, the Netherlands (J.M.C.).</nlm:affiliation><orgName type="university">Université McMaster</orgName><country>Canada</country><placeName><settlement type="city">Hamilton (Ontario)</settlement><region type="state">Ontario</region></placeName></affiliation></author><author><name sortKey="Mundl, Hardi" sort="Mundl, Hardi" uniqKey="Mundl H" first="Hardi" last="Mundl">Hardi Mundl</name><affiliation wicri:level="4"><nlm:affiliation>From the Population Health Research Institute, McMaster University, Hamilton Health Sciences, Ontario, Canada (K.S.P., J.B., B.S., M.G., S.J.C., R.G.H.); Department of Cardiovascular Sciences, University of Leuven, Belgium (T.V.); Bayer-Pharma AG, Wuppertal, Germany (H.M.); Instituto Nacional de Neurologia y Neurocirugia, Mexico D.F., Mexico (M.A.B.); University of Galway, Ireland (M.J.O.); Institute for Neurological Research, Fundacion para la Lucha contra las Enfermedades Neurologicas de la Infancia (FLENI), Buenos Aires, Argentina (M.G.-S.); School of Medicine and Pharmacology, University of Western Australia, Sir Charles Gairdner Hospital, Perth, Australia (G.J.H.); Department of Neurology, Seoul National University Hospital, Korea (B.-W.Y.); Medical City Hospital, Manila, Philippines (A.R.); Department of Neurology, Bichat Hospital, Paris, France (P.L.); Centro Hospitalar e Universitário de Coimbra, Portugal (J.S.-F.); Pirogov Russian National Research Medical University, Moscow, Russia (N.S.); Universitair Ziekenhuis Brussel, Belgium (R.B.); Santa Casa de São Paulo, Medical School, Brazil (R.J.G.); Department of Neurology, Hospital of the University of Pennsylvania, Philadelphia (S.E.K.); Emergency Department Stroke Unit, Hospital Policlinico Umberto I, Department of Neurology and Psychiatry, 'Sapienza' University, Rome, Italy (A.P.); Department of Neurology, University Hospital Heidelberg, Germany (P.V.); Department of Neurology, Tokyo Women's Medical University, Japan (K.K.); Department of Neurology, Beijing Tiantan Hospital, Capital Medical University, China (Y.W.); Institute of Neuroscience & Psychology, University of Glasgow, Queen Elizabeth University Hospital, United Kingdom (K.M.); and Academic Medical Center, Amsterdam, the Netherlands (J.M.C.).</nlm:affiliation><orgName type="university">Université McMaster</orgName><country>Canada</country><placeName><settlement type="city">Hamilton (Ontario)</settlement><region type="state">Ontario</region></placeName></affiliation></author><author><name sortKey="Giruparajah, Mohana" sort="Giruparajah, Mohana" uniqKey="Giruparajah M" first="Mohana" last="Giruparajah">Mohana Giruparajah</name><affiliation wicri:level="4"><nlm:affiliation>From the Population Health Research Institute, McMaster University, Hamilton Health Sciences, Ontario, Canada (K.S.P., J.B., B.S., M.G., S.J.C., R.G.H.); Department of Cardiovascular Sciences, University of Leuven, Belgium (T.V.); Bayer-Pharma AG, Wuppertal, Germany (H.M.); Instituto Nacional de Neurologia y Neurocirugia, Mexico D.F., Mexico (M.A.B.); University of Galway, Ireland (M.J.O.); Institute for Neurological Research, Fundacion para la Lucha contra las Enfermedades Neurologicas de la Infancia (FLENI), Buenos Aires, Argentina (M.G.-S.); School of Medicine and Pharmacology, University of Western Australia, Sir Charles Gairdner Hospital, Perth, Australia (G.J.H.); Department of Neurology, Seoul National University Hospital, Korea (B.-W.Y.); Medical City Hospital, Manila, Philippines (A.R.); Department of Neurology, Bichat Hospital, Paris, France (P.L.); Centro Hospitalar e Universitário de Coimbra, Portugal (J.S.-F.); Pirogov Russian National Research Medical University, Moscow, Russia (N.S.); Universitair Ziekenhuis Brussel, Belgium (R.B.); Santa Casa de São Paulo, Medical School, Brazil (R.J.G.); Department of Neurology, Hospital of the University of Pennsylvania, Philadelphia (S.E.K.); Emergency Department Stroke Unit, Hospital Policlinico Umberto I, Department of Neurology and Psychiatry, 'Sapienza' University, Rome, Italy (A.P.); Department of Neurology, University Hospital Heidelberg, Germany (P.V.); Department of Neurology, Tokyo Women's Medical University, Japan (K.K.); Department of Neurology, Beijing Tiantan Hospital, Capital Medical University, China (Y.W.); Institute of Neuroscience & Psychology, University of Glasgow, Queen Elizabeth University Hospital, United Kingdom (K.M.); and Academic Medical Center, Amsterdam, the Netherlands (J.M.C.).</nlm:affiliation><orgName type="university">Université McMaster</orgName><country>Canada</country><placeName><settlement type="city">Hamilton (Ontario)</settlement><region type="state">Ontario</region></placeName></affiliation></author><author><name sortKey="Barboza, Miguel A" sort="Barboza, Miguel A" uniqKey="Barboza M" first="Miguel A" last="Barboza">Miguel A. Barboza</name><affiliation wicri:level="4"><nlm:affiliation>From the Population Health Research Institute, McMaster University, Hamilton Health Sciences, Ontario, Canada (K.S.P., J.B., B.S., M.G., S.J.C., R.G.H.); Department of Cardiovascular Sciences, University of Leuven, Belgium (T.V.); Bayer-Pharma AG, Wuppertal, Germany (H.M.); Instituto Nacional de Neurologia y Neurocirugia, Mexico D.F., Mexico (M.A.B.); University of Galway, Ireland (M.J.O.); Institute for Neurological Research, Fundacion para la Lucha contra las Enfermedades Neurologicas de la Infancia (FLENI), Buenos Aires, Argentina (M.G.-S.); School of Medicine and Pharmacology, University of Western Australia, Sir Charles Gairdner Hospital, Perth, Australia (G.J.H.); Department of Neurology, Seoul National University Hospital, Korea (B.-W.Y.); Medical City Hospital, Manila, Philippines (A.R.); Department of Neurology, Bichat Hospital, Paris, France (P.L.); Centro Hospitalar e Universitário de Coimbra, Portugal (J.S.-F.); Pirogov Russian National Research Medical University, Moscow, Russia (N.S.); Universitair Ziekenhuis Brussel, Belgium (R.B.); Santa Casa de São Paulo, Medical School, Brazil (R.J.G.); Department of Neurology, Hospital of the University of Pennsylvania, Philadelphia (S.E.K.); Emergency Department Stroke Unit, Hospital Policlinico Umberto I, Department of Neurology and Psychiatry, 'Sapienza' University, Rome, Italy (A.P.); Department of Neurology, University Hospital Heidelberg, Germany (P.V.); Department of Neurology, Tokyo Women's Medical University, Japan (K.K.); Department of Neurology, Beijing Tiantan Hospital, Capital Medical University, China (Y.W.); Institute of Neuroscience & Psychology, University of Glasgow, Queen Elizabeth University Hospital, United Kingdom (K.M.); and Academic Medical Center, Amsterdam, the Netherlands (J.M.C.).</nlm:affiliation><orgName type="university">Université McMaster</orgName><country>Canada</country><placeName><settlement type="city">Hamilton (Ontario)</settlement><region type="state">Ontario</region></placeName></affiliation></author><author><name sortKey="O Donnell, Martin J" sort="O Donnell, Martin J" uniqKey="O Donnell M" first="Martin J" last="O'Donnell">Martin J. O'Donnell</name><affiliation wicri:level="4"><nlm:affiliation>From the Population Health Research Institute, McMaster University, Hamilton Health Sciences, Ontario, Canada (K.S.P., J.B., B.S., M.G., S.J.C., R.G.H.); Department of Cardiovascular Sciences, University of Leuven, Belgium (T.V.); Bayer-Pharma AG, Wuppertal, Germany (H.M.); Instituto Nacional de Neurologia y Neurocirugia, Mexico D.F., Mexico (M.A.B.); University of Galway, Ireland (M.J.O.); Institute for Neurological Research, Fundacion para la Lucha contra las Enfermedades Neurologicas de la Infancia (FLENI), Buenos Aires, Argentina (M.G.-S.); School of Medicine and Pharmacology, University of Western Australia, Sir Charles Gairdner Hospital, Perth, Australia (G.J.H.); Department of Neurology, Seoul National University Hospital, Korea (B.-W.Y.); Medical City Hospital, Manila, Philippines (A.R.); Department of Neurology, Bichat Hospital, Paris, France (P.L.); Centro Hospitalar e Universitário de Coimbra, Portugal (J.S.-F.); Pirogov Russian National Research Medical University, Moscow, Russia (N.S.); Universitair Ziekenhuis Brussel, Belgium (R.B.); Santa Casa de São Paulo, Medical School, Brazil (R.J.G.); Department of Neurology, Hospital of the University of Pennsylvania, Philadelphia (S.E.K.); Emergency Department Stroke Unit, Hospital Policlinico Umberto I, Department of Neurology and Psychiatry, 'Sapienza' University, Rome, Italy (A.P.); Department of Neurology, University Hospital Heidelberg, Germany (P.V.); Department of Neurology, Tokyo Women's Medical University, Japan (K.K.); Department of Neurology, Beijing Tiantan Hospital, Capital Medical University, China (Y.W.); Institute of Neuroscience & Psychology, University of Glasgow, Queen Elizabeth University Hospital, United Kingdom (K.M.); and Academic Medical Center, Amsterdam, the Netherlands (J.M.C.).</nlm:affiliation><orgName type="university">Université McMaster</orgName><country>Canada</country><placeName><settlement type="city">Hamilton (Ontario)</settlement><region type="state">Ontario</region></placeName></affiliation></author><author><name sortKey="Gomez Schneider, Maia" sort="Gomez Schneider, Maia" uniqKey="Gomez Schneider M" first="Maia" last="Gomez-Schneider">Maia Gomez-Schneider</name><affiliation wicri:level="4"><nlm:affiliation>From the Population Health Research Institute, McMaster University, Hamilton Health Sciences, Ontario, Canada (K.S.P., J.B., B.S., M.G., S.J.C., R.G.H.); Department of Cardiovascular Sciences, University of Leuven, Belgium (T.V.); Bayer-Pharma AG, Wuppertal, Germany (H.M.); Instituto Nacional de Neurologia y Neurocirugia, Mexico D.F., Mexico (M.A.B.); University of Galway, Ireland (M.J.O.); Institute for Neurological Research, Fundacion para la Lucha contra las Enfermedades Neurologicas de la Infancia (FLENI), Buenos Aires, Argentina (M.G.-S.); School of Medicine and Pharmacology, University of Western Australia, Sir Charles Gairdner Hospital, Perth, Australia (G.J.H.); Department of Neurology, Seoul National University Hospital, Korea (B.-W.Y.); Medical City Hospital, Manila, Philippines (A.R.); Department of Neurology, Bichat Hospital, Paris, France (P.L.); Centro Hospitalar e Universitário de Coimbra, Portugal (J.S.-F.); Pirogov Russian National Research Medical University, Moscow, Russia (N.S.); Universitair Ziekenhuis Brussel, Belgium (R.B.); Santa Casa de São Paulo, Medical School, Brazil (R.J.G.); Department of Neurology, Hospital of the University of Pennsylvania, Philadelphia (S.E.K.); Emergency Department Stroke Unit, Hospital Policlinico Umberto I, Department of Neurology and Psychiatry, 'Sapienza' University, Rome, Italy (A.P.); Department of Neurology, University Hospital Heidelberg, Germany (P.V.); Department of Neurology, Tokyo Women's Medical University, Japan (K.K.); Department of Neurology, Beijing Tiantan Hospital, Capital Medical University, China (Y.W.); Institute of Neuroscience & Psychology, University of Glasgow, Queen Elizabeth University Hospital, United Kingdom (K.M.); and Academic Medical Center, Amsterdam, the Netherlands (J.M.C.).</nlm:affiliation><orgName type="university">Université McMaster</orgName><country>Canada</country><placeName><settlement type="city">Hamilton (Ontario)</settlement><region type="state">Ontario</region></placeName></affiliation></author><author><name sortKey="Hankey, Graeme J" sort="Hankey, Graeme J" uniqKey="Hankey G" first="Graeme J" last="Hankey">Graeme J. Hankey</name><affiliation wicri:level="4"><nlm:affiliation>From the Population Health Research Institute, McMaster University, Hamilton Health Sciences, Ontario, Canada (K.S.P., J.B., B.S., M.G., S.J.C., R.G.H.); Department of Cardiovascular Sciences, University of Leuven, Belgium (T.V.); Bayer-Pharma AG, Wuppertal, Germany (H.M.); Instituto Nacional de Neurologia y Neurocirugia, Mexico D.F., Mexico (M.A.B.); University of Galway, Ireland (M.J.O.); Institute for Neurological Research, Fundacion para la Lucha contra las Enfermedades Neurologicas de la Infancia (FLENI), Buenos Aires, Argentina (M.G.-S.); School of Medicine and Pharmacology, University of Western Australia, Sir Charles Gairdner Hospital, Perth, Australia (G.J.H.); Department of Neurology, Seoul National University Hospital, Korea (B.-W.Y.); Medical City Hospital, Manila, Philippines (A.R.); Department of Neurology, Bichat Hospital, Paris, France (P.L.); Centro Hospitalar e Universitário de Coimbra, Portugal (J.S.-F.); Pirogov Russian National Research Medical University, Moscow, Russia (N.S.); Universitair Ziekenhuis Brussel, Belgium (R.B.); Santa Casa de São Paulo, Medical School, Brazil (R.J.G.); Department of Neurology, Hospital of the University of Pennsylvania, Philadelphia (S.E.K.); Emergency Department Stroke Unit, Hospital Policlinico Umberto I, Department of Neurology and Psychiatry, 'Sapienza' University, Rome, Italy (A.P.); Department of Neurology, University Hospital Heidelberg, Germany (P.V.); Department of Neurology, Tokyo Women's Medical University, Japan (K.K.); Department of Neurology, Beijing Tiantan Hospital, Capital Medical University, China (Y.W.); Institute of Neuroscience & Psychology, University of Glasgow, Queen Elizabeth University Hospital, United Kingdom (K.M.); and Academic Medical Center, Amsterdam, the Netherlands (J.M.C.).</nlm:affiliation><orgName type="university">Université McMaster</orgName><country>Canada</country><placeName><settlement type="city">Hamilton (Ontario)</settlement><region type="state">Ontario</region></placeName></affiliation></author><author><name sortKey="Yoon, Byung Woo" sort="Yoon, Byung Woo" uniqKey="Yoon B" first="Byung-Woo" last="Yoon">Byung-Woo Yoon</name><affiliation wicri:level="4"><nlm:affiliation>From the Population Health Research Institute, McMaster University, Hamilton Health Sciences, Ontario, Canada (K.S.P., J.B., B.S., M.G., S.J.C., R.G.H.); Department of Cardiovascular Sciences, University of Leuven, Belgium (T.V.); Bayer-Pharma AG, Wuppertal, Germany (H.M.); Instituto Nacional de Neurologia y Neurocirugia, Mexico D.F., Mexico (M.A.B.); University of Galway, Ireland (M.J.O.); Institute for Neurological Research, Fundacion para la Lucha contra las Enfermedades Neurologicas de la Infancia (FLENI), Buenos Aires, Argentina (M.G.-S.); School of Medicine and Pharmacology, University of Western Australia, Sir Charles Gairdner Hospital, Perth, Australia (G.J.H.); Department of Neurology, Seoul National University Hospital, Korea (B.-W.Y.); Medical City Hospital, Manila, Philippines (A.R.); Department of Neurology, Bichat Hospital, Paris, France (P.L.); Centro Hospitalar e Universitário de Coimbra, Portugal (J.S.-F.); Pirogov Russian National Research Medical University, Moscow, Russia (N.S.); Universitair Ziekenhuis Brussel, Belgium (R.B.); Santa Casa de São Paulo, Medical School, Brazil (R.J.G.); Department of Neurology, Hospital of the University of Pennsylvania, Philadelphia (S.E.K.); Emergency Department Stroke Unit, Hospital Policlinico Umberto I, Department of Neurology and Psychiatry, 'Sapienza' University, Rome, Italy (A.P.); Department of Neurology, University Hospital Heidelberg, Germany (P.V.); Department of Neurology, Tokyo Women's Medical University, Japan (K.K.); Department of Neurology, Beijing Tiantan Hospital, Capital Medical University, China (Y.W.); Institute of Neuroscience & Psychology, University of Glasgow, Queen Elizabeth University Hospital, United Kingdom (K.M.); and Academic Medical Center, Amsterdam, the Netherlands (J.M.C.).</nlm:affiliation><orgName type="university">Université McMaster</orgName><country>Canada</country><placeName><settlement type="city">Hamilton (Ontario)</settlement><region type="state">Ontario</region></placeName></affiliation></author><author><name sortKey="Roxas, Artemio" sort="Roxas, Artemio" uniqKey="Roxas A" first="Artemio" last="Roxas">Artemio Roxas</name><affiliation wicri:level="4"><nlm:affiliation>From the Population Health Research Institute, McMaster University, Hamilton Health Sciences, Ontario, Canada (K.S.P., J.B., B.S., M.G., S.J.C., R.G.H.); Department of Cardiovascular Sciences, University of Leuven, Belgium (T.V.); Bayer-Pharma AG, Wuppertal, Germany (H.M.); Instituto Nacional de Neurologia y Neurocirugia, Mexico D.F., Mexico (M.A.B.); University of Galway, Ireland (M.J.O.); Institute for Neurological Research, Fundacion para la Lucha contra las Enfermedades Neurologicas de la Infancia (FLENI), Buenos Aires, Argentina (M.G.-S.); School of Medicine and Pharmacology, University of Western Australia, Sir Charles Gairdner Hospital, Perth, Australia (G.J.H.); Department of Neurology, Seoul National University Hospital, Korea (B.-W.Y.); Medical City Hospital, Manila, Philippines (A.R.); Department of Neurology, Bichat Hospital, Paris, France (P.L.); Centro Hospitalar e Universitário de Coimbra, Portugal (J.S.-F.); Pirogov Russian National Research Medical University, Moscow, Russia (N.S.); Universitair Ziekenhuis Brussel, Belgium (R.B.); Santa Casa de São Paulo, Medical School, Brazil (R.J.G.); Department of Neurology, Hospital of the University of Pennsylvania, Philadelphia (S.E.K.); Emergency Department Stroke Unit, Hospital Policlinico Umberto I, Department of Neurology and Psychiatry, 'Sapienza' University, Rome, Italy (A.P.); Department of Neurology, University Hospital Heidelberg, Germany (P.V.); Department of Neurology, Tokyo Women's Medical University, Japan (K.K.); Department of Neurology, Beijing Tiantan Hospital, Capital Medical University, China (Y.W.); Institute of Neuroscience & Psychology, University of Glasgow, Queen Elizabeth University Hospital, United Kingdom (K.M.); and Academic Medical Center, Amsterdam, the Netherlands (J.M.C.).</nlm:affiliation><orgName type="university">Université McMaster</orgName><country>Canada</country><placeName><settlement type="city">Hamilton (Ontario)</settlement><region type="state">Ontario</region></placeName></affiliation></author><author><name sortKey="Lavallee, Philippa" sort="Lavallee, Philippa" uniqKey="Lavallee P" first="Philippa" last="Lavallee">Philippa Lavallee</name><affiliation wicri:level="4"><nlm:affiliation>From the Population Health Research Institute, McMaster University, Hamilton Health Sciences, Ontario, Canada (K.S.P., J.B., B.S., M.G., S.J.C., R.G.H.); Department of Cardiovascular Sciences, University of Leuven, Belgium (T.V.); Bayer-Pharma AG, Wuppertal, Germany (H.M.); Instituto Nacional de Neurologia y Neurocirugia, Mexico D.F., Mexico (M.A.B.); University of Galway, Ireland (M.J.O.); Institute for Neurological Research, Fundacion para la Lucha contra las Enfermedades Neurologicas de la Infancia (FLENI), Buenos Aires, Argentina (M.G.-S.); School of Medicine and Pharmacology, University of Western Australia, Sir Charles Gairdner Hospital, Perth, Australia (G.J.H.); Department of Neurology, Seoul National University Hospital, Korea (B.-W.Y.); Medical City Hospital, Manila, Philippines (A.R.); Department of Neurology, Bichat Hospital, Paris, France (P.L.); Centro Hospitalar e Universitário de Coimbra, Portugal (J.S.-F.); Pirogov Russian National Research Medical University, Moscow, Russia (N.S.); Universitair Ziekenhuis Brussel, Belgium (R.B.); Santa Casa de São Paulo, Medical School, Brazil (R.J.G.); Department of Neurology, Hospital of the University of Pennsylvania, Philadelphia (S.E.K.); Emergency Department Stroke Unit, Hospital Policlinico Umberto I, Department of Neurology and Psychiatry, 'Sapienza' University, Rome, Italy (A.P.); Department of Neurology, University Hospital Heidelberg, Germany (P.V.); Department of Neurology, Tokyo Women's Medical University, Japan (K.K.); Department of Neurology, Beijing Tiantan Hospital, Capital Medical University, China (Y.W.); Institute of Neuroscience & Psychology, University of Glasgow, Queen Elizabeth University Hospital, United Kingdom (K.M.); and Academic Medical Center, Amsterdam, the Netherlands (J.M.C.).</nlm:affiliation><orgName type="university">Université McMaster</orgName><country>Canada</country><placeName><settlement type="city">Hamilton (Ontario)</settlement><region type="state">Ontario</region></placeName></affiliation></author><author><name sortKey="Sargento Freitas, Joao" sort="Sargento Freitas, Joao" uniqKey="Sargento Freitas J" first="Joao" last="Sargento-Freitas">Joao Sargento-Freitas</name><affiliation wicri:level="4"><nlm:affiliation>From the Population Health Research Institute, McMaster University, Hamilton Health Sciences, Ontario, Canada (K.S.P., J.B., B.S., M.G., S.J.C., R.G.H.); Department of Cardiovascular Sciences, University of Leuven, Belgium (T.V.); Bayer-Pharma AG, Wuppertal, Germany (H.M.); Instituto Nacional de Neurologia y Neurocirugia, Mexico D.F., Mexico (M.A.B.); University of Galway, Ireland (M.J.O.); Institute for Neurological Research, Fundacion para la Lucha contra las Enfermedades Neurologicas de la Infancia (FLENI), Buenos Aires, Argentina (M.G.-S.); School of Medicine and Pharmacology, University of Western Australia, Sir Charles Gairdner Hospital, Perth, Australia (G.J.H.); Department of Neurology, Seoul National University Hospital, Korea (B.-W.Y.); Medical City Hospital, Manila, Philippines (A.R.); Department of Neurology, Bichat Hospital, Paris, France (P.L.); Centro Hospitalar e Universitário de Coimbra, Portugal (J.S.-F.); Pirogov Russian National Research Medical University, Moscow, Russia (N.S.); Universitair Ziekenhuis Brussel, Belgium (R.B.); Santa Casa de São Paulo, Medical School, Brazil (R.J.G.); Department of Neurology, Hospital of the University of Pennsylvania, Philadelphia (S.E.K.); Emergency Department Stroke Unit, Hospital Policlinico Umberto I, Department of Neurology and Psychiatry, 'Sapienza' University, Rome, Italy (A.P.); Department of Neurology, University Hospital Heidelberg, Germany (P.V.); Department of Neurology, Tokyo Women's Medical University, Japan (K.K.); Department of Neurology, Beijing Tiantan Hospital, Capital Medical University, China (Y.W.); Institute of Neuroscience & Psychology, University of Glasgow, Queen Elizabeth University Hospital, United Kingdom (K.M.); and Academic Medical Center, Amsterdam, the Netherlands (J.M.C.).</nlm:affiliation><orgName type="university">Université McMaster</orgName><country>Canada</country><placeName><settlement type="city">Hamilton (Ontario)</settlement><region type="state">Ontario</region></placeName></affiliation></author><author><name sortKey="Shamalov, Nikolay" sort="Shamalov, Nikolay" uniqKey="Shamalov N" first="Nikolay" last="Shamalov">Nikolay Shamalov</name><affiliation wicri:level="4"><nlm:affiliation>From the Population Health Research Institute, McMaster University, Hamilton Health Sciences, Ontario, Canada (K.S.P., J.B., B.S., M.G., S.J.C., R.G.H.); Department of Cardiovascular Sciences, University of Leuven, Belgium (T.V.); Bayer-Pharma AG, Wuppertal, Germany (H.M.); Instituto Nacional de Neurologia y Neurocirugia, Mexico D.F., Mexico (M.A.B.); University of Galway, Ireland (M.J.O.); Institute for Neurological Research, Fundacion para la Lucha contra las Enfermedades Neurologicas de la Infancia (FLENI), Buenos Aires, Argentina (M.G.-S.); School of Medicine and Pharmacology, University of Western Australia, Sir Charles Gairdner Hospital, Perth, Australia (G.J.H.); Department of Neurology, Seoul National University Hospital, Korea (B.-W.Y.); Medical City Hospital, Manila, Philippines (A.R.); Department of Neurology, Bichat Hospital, Paris, France (P.L.); Centro Hospitalar e Universitário de Coimbra, Portugal (J.S.-F.); Pirogov Russian National Research Medical University, Moscow, Russia (N.S.); Universitair Ziekenhuis Brussel, Belgium (R.B.); Santa Casa de São Paulo, Medical School, Brazil (R.J.G.); Department of Neurology, Hospital of the University of Pennsylvania, Philadelphia (S.E.K.); Emergency Department Stroke Unit, Hospital Policlinico Umberto I, Department of Neurology and Psychiatry, 'Sapienza' University, Rome, Italy (A.P.); Department of Neurology, University Hospital Heidelberg, Germany (P.V.); Department of Neurology, Tokyo Women's Medical University, Japan (K.K.); Department of Neurology, Beijing Tiantan Hospital, Capital Medical University, China (Y.W.); Institute of Neuroscience & Psychology, University of Glasgow, Queen Elizabeth University Hospital, United Kingdom (K.M.); and Academic Medical Center, Amsterdam, the Netherlands (J.M.C.).</nlm:affiliation><orgName type="university">Université McMaster</orgName><country>Canada</country><placeName><settlement type="city">Hamilton (Ontario)</settlement><region type="state">Ontario</region></placeName></affiliation></author><author><name sortKey="Brouns, Raf" sort="Brouns, Raf" uniqKey="Brouns R" first="Raf" last="Brouns">Raf Brouns</name><affiliation wicri:level="4"><nlm:affiliation>From the Population Health Research Institute, McMaster University, Hamilton Health Sciences, Ontario, Canada (K.S.P., J.B., B.S., M.G., S.J.C., R.G.H.); Department of Cardiovascular Sciences, University of Leuven, Belgium (T.V.); Bayer-Pharma AG, Wuppertal, Germany (H.M.); Instituto Nacional de Neurologia y Neurocirugia, Mexico D.F., Mexico (M.A.B.); University of Galway, Ireland (M.J.O.); Institute for Neurological Research, Fundacion para la Lucha contra las Enfermedades Neurologicas de la Infancia (FLENI), Buenos Aires, Argentina (M.G.-S.); School of Medicine and Pharmacology, University of Western Australia, Sir Charles Gairdner Hospital, Perth, Australia (G.J.H.); Department of Neurology, Seoul National University Hospital, Korea (B.-W.Y.); Medical City Hospital, Manila, Philippines (A.R.); Department of Neurology, Bichat Hospital, Paris, France (P.L.); Centro Hospitalar e Universitário de Coimbra, Portugal (J.S.-F.); Pirogov Russian National Research Medical University, Moscow, Russia (N.S.); Universitair Ziekenhuis Brussel, Belgium (R.B.); Santa Casa de São Paulo, Medical School, Brazil (R.J.G.); Department of Neurology, Hospital of the University of Pennsylvania, Philadelphia (S.E.K.); Emergency Department Stroke Unit, Hospital Policlinico Umberto I, Department of Neurology and Psychiatry, 'Sapienza' University, Rome, Italy (A.P.); Department of Neurology, University Hospital Heidelberg, Germany (P.V.); Department of Neurology, Tokyo Women's Medical University, Japan (K.K.); Department of Neurology, Beijing Tiantan Hospital, Capital Medical University, China (Y.W.); Institute of Neuroscience & Psychology, University of Glasgow, Queen Elizabeth University Hospital, United Kingdom (K.M.); and Academic Medical Center, Amsterdam, the Netherlands (J.M.C.).</nlm:affiliation><orgName type="university">Université McMaster</orgName><country>Canada</country><placeName><settlement type="city">Hamilton (Ontario)</settlement><region type="state">Ontario</region></placeName></affiliation></author><author><name sortKey="Gagliardi, Rubens J" sort="Gagliardi, Rubens J" uniqKey="Gagliardi R" first="Rubens J" last="Gagliardi">Rubens J. Gagliardi</name><affiliation wicri:level="4"><nlm:affiliation>From the Population Health Research Institute, McMaster University, Hamilton Health Sciences, Ontario, Canada (K.S.P., J.B., B.S., M.G., S.J.C., R.G.H.); Department of Cardiovascular Sciences, University of Leuven, Belgium (T.V.); Bayer-Pharma AG, Wuppertal, Germany (H.M.); Instituto Nacional de Neurologia y Neurocirugia, Mexico D.F., Mexico (M.A.B.); University of Galway, Ireland (M.J.O.); Institute for Neurological Research, Fundacion para la Lucha contra las Enfermedades Neurologicas de la Infancia (FLENI), Buenos Aires, Argentina (M.G.-S.); School of Medicine and Pharmacology, University of Western Australia, Sir Charles Gairdner Hospital, Perth, Australia (G.J.H.); Department of Neurology, Seoul National University Hospital, Korea (B.-W.Y.); Medical City Hospital, Manila, Philippines (A.R.); Department of Neurology, Bichat Hospital, Paris, France (P.L.); Centro Hospitalar e Universitário de Coimbra, Portugal (J.S.-F.); Pirogov Russian National Research Medical University, Moscow, Russia (N.S.); Universitair Ziekenhuis Brussel, Belgium (R.B.); Santa Casa de São Paulo, Medical School, Brazil (R.J.G.); Department of Neurology, Hospital of the University of Pennsylvania, Philadelphia (S.E.K.); Emergency Department Stroke Unit, Hospital Policlinico Umberto I, Department of Neurology and Psychiatry, 'Sapienza' University, Rome, Italy (A.P.); Department of Neurology, University Hospital Heidelberg, Germany (P.V.); Department of Neurology, Tokyo Women's Medical University, Japan (K.K.); Department of Neurology, Beijing Tiantan Hospital, Capital Medical University, China (Y.W.); Institute of Neuroscience & Psychology, University of Glasgow, Queen Elizabeth University Hospital, United Kingdom (K.M.); and Academic Medical Center, Amsterdam, the Netherlands (J.M.C.).</nlm:affiliation><orgName type="university">Université McMaster</orgName><country>Canada</country><placeName><settlement type="city">Hamilton (Ontario)</settlement><region type="state">Ontario</region></placeName></affiliation></author><author><name sortKey="Kasner, Scott E" sort="Kasner, Scott E" uniqKey="Kasner S" first="Scott E" last="Kasner">Scott E. Kasner</name><affiliation wicri:level="4"><nlm:affiliation>From the Population Health Research Institute, McMaster University, Hamilton Health Sciences, Ontario, Canada (K.S.P., J.B., B.S., M.G., S.J.C., R.G.H.); Department of Cardiovascular Sciences, University of Leuven, Belgium (T.V.); Bayer-Pharma AG, Wuppertal, Germany (H.M.); Instituto Nacional de Neurologia y Neurocirugia, Mexico D.F., Mexico (M.A.B.); University of Galway, Ireland (M.J.O.); Institute for Neurological Research, Fundacion para la Lucha contra las Enfermedades Neurologicas de la Infancia (FLENI), Buenos Aires, Argentina (M.G.-S.); School of Medicine and Pharmacology, University of Western Australia, Sir Charles Gairdner Hospital, Perth, Australia (G.J.H.); Department of Neurology, Seoul National University Hospital, Korea (B.-W.Y.); Medical City Hospital, Manila, Philippines (A.R.); Department of Neurology, Bichat Hospital, Paris, France (P.L.); Centro Hospitalar e Universitário de Coimbra, Portugal (J.S.-F.); Pirogov Russian National Research Medical University, Moscow, Russia (N.S.); Universitair Ziekenhuis Brussel, Belgium (R.B.); Santa Casa de São Paulo, Medical School, Brazil (R.J.G.); Department of Neurology, Hospital of the University of Pennsylvania, Philadelphia (S.E.K.); Emergency Department Stroke Unit, Hospital Policlinico Umberto I, Department of Neurology and Psychiatry, 'Sapienza' University, Rome, Italy (A.P.); Department of Neurology, University Hospital Heidelberg, Germany (P.V.); Department of Neurology, Tokyo Women's Medical University, Japan (K.K.); Department of Neurology, Beijing Tiantan Hospital, Capital Medical University, China (Y.W.); Institute of Neuroscience & Psychology, University of Glasgow, Queen Elizabeth University Hospital, United Kingdom (K.M.); and Academic Medical Center, Amsterdam, the Netherlands (J.M.C.).</nlm:affiliation><orgName type="university">Université McMaster</orgName><country>Canada</country><placeName><settlement type="city">Hamilton (Ontario)</settlement><region type="state">Ontario</region></placeName></affiliation></author><author><name sortKey="Pieroni, Alessio" sort="Pieroni, Alessio" uniqKey="Pieroni A" first="Alessio" last="Pieroni">Alessio Pieroni</name><affiliation wicri:level="4"><nlm:affiliation>From the Population Health Research Institute, McMaster University, Hamilton Health Sciences, Ontario, Canada (K.S.P., J.B., B.S., M.G., S.J.C., R.G.H.); Department of Cardiovascular Sciences, University of Leuven, Belgium (T.V.); Bayer-Pharma AG, Wuppertal, Germany (H.M.); Instituto Nacional de Neurologia y Neurocirugia, Mexico D.F., Mexico (M.A.B.); University of Galway, Ireland (M.J.O.); Institute for Neurological Research, Fundacion para la Lucha contra las Enfermedades Neurologicas de la Infancia (FLENI), Buenos Aires, Argentina (M.G.-S.); School of Medicine and Pharmacology, University of Western Australia, Sir Charles Gairdner Hospital, Perth, Australia (G.J.H.); Department of Neurology, Seoul National University Hospital, Korea (B.-W.Y.); Medical City Hospital, Manila, Philippines (A.R.); Department of Neurology, Bichat Hospital, Paris, France (P.L.); Centro Hospitalar e Universitário de Coimbra, Portugal (J.S.-F.); Pirogov Russian National Research Medical University, Moscow, Russia (N.S.); Universitair Ziekenhuis Brussel, Belgium (R.B.); Santa Casa de São Paulo, Medical School, Brazil (R.J.G.); Department of Neurology, Hospital of the University of Pennsylvania, Philadelphia (S.E.K.); Emergency Department Stroke Unit, Hospital Policlinico Umberto I, Department of Neurology and Psychiatry, 'Sapienza' University, Rome, Italy (A.P.); Department of Neurology, University Hospital Heidelberg, Germany (P.V.); Department of Neurology, Tokyo Women's Medical University, Japan (K.K.); Department of Neurology, Beijing Tiantan Hospital, Capital Medical University, China (Y.W.); Institute of Neuroscience & Psychology, University of Glasgow, Queen Elizabeth University Hospital, United Kingdom (K.M.); and Academic Medical Center, Amsterdam, the Netherlands (J.M.C.).</nlm:affiliation><orgName type="university">Université McMaster</orgName><country>Canada</country><placeName><settlement type="city">Hamilton (Ontario)</settlement><region type="state">Ontario</region></placeName></affiliation></author><author><name sortKey="Vermehren, Philipp" sort="Vermehren, Philipp" uniqKey="Vermehren P" first="Philipp" last="Vermehren">Philipp Vermehren</name><affiliation wicri:level="4"><nlm:affiliation>From the Population Health Research Institute, McMaster University, Hamilton Health Sciences, Ontario, Canada (K.S.P., J.B., B.S., M.G., S.J.C., R.G.H.); Department of Cardiovascular Sciences, University of Leuven, Belgium (T.V.); Bayer-Pharma AG, Wuppertal, Germany (H.M.); Instituto Nacional de Neurologia y Neurocirugia, Mexico D.F., Mexico (M.A.B.); University of Galway, Ireland (M.J.O.); Institute for Neurological Research, Fundacion para la Lucha contra las Enfermedades Neurologicas de la Infancia (FLENI), Buenos Aires, Argentina (M.G.-S.); School of Medicine and Pharmacology, University of Western Australia, Sir Charles Gairdner Hospital, Perth, Australia (G.J.H.); Department of Neurology, Seoul National University Hospital, Korea (B.-W.Y.); Medical City Hospital, Manila, Philippines (A.R.); Department of Neurology, Bichat Hospital, Paris, France (P.L.); Centro Hospitalar e Universitário de Coimbra, Portugal (J.S.-F.); Pirogov Russian National Research Medical University, Moscow, Russia (N.S.); Universitair Ziekenhuis Brussel, Belgium (R.B.); Santa Casa de São Paulo, Medical School, Brazil (R.J.G.); Department of Neurology, Hospital of the University of Pennsylvania, Philadelphia (S.E.K.); Emergency Department Stroke Unit, Hospital Policlinico Umberto I, Department of Neurology and Psychiatry, 'Sapienza' University, Rome, Italy (A.P.); Department of Neurology, University Hospital Heidelberg, Germany (P.V.); Department of Neurology, Tokyo Women's Medical University, Japan (K.K.); Department of Neurology, Beijing Tiantan Hospital, Capital Medical University, China (Y.W.); Institute of Neuroscience & Psychology, University of Glasgow, Queen Elizabeth University Hospital, United Kingdom (K.M.); and Academic Medical Center, Amsterdam, the Netherlands (J.M.C.).</nlm:affiliation><orgName type="university">Université McMaster</orgName><country>Canada</country><placeName><settlement type="city">Hamilton (Ontario)</settlement><region type="state">Ontario</region></placeName></affiliation></author><author><name sortKey="Kitagawa, Kazuo" sort="Kitagawa, Kazuo" uniqKey="Kitagawa K" first="Kazuo" last="Kitagawa">Kazuo Kitagawa</name><affiliation wicri:level="4"><nlm:affiliation>From the Population Health Research Institute, McMaster University, Hamilton Health Sciences, Ontario, Canada (K.S.P., J.B., B.S., M.G., S.J.C., R.G.H.); Department of Cardiovascular Sciences, University of Leuven, Belgium (T.V.); Bayer-Pharma AG, Wuppertal, Germany (H.M.); Instituto Nacional de Neurologia y Neurocirugia, Mexico D.F., Mexico (M.A.B.); University of Galway, Ireland (M.J.O.); Institute for Neurological Research, Fundacion para la Lucha contra las Enfermedades Neurologicas de la Infancia (FLENI), Buenos Aires, Argentina (M.G.-S.); School of Medicine and Pharmacology, University of Western Australia, Sir Charles Gairdner Hospital, Perth, Australia (G.J.H.); Department of Neurology, Seoul National University Hospital, Korea (B.-W.Y.); Medical City Hospital, Manila, Philippines (A.R.); Department of Neurology, Bichat Hospital, Paris, France (P.L.); Centro Hospitalar e Universitário de Coimbra, Portugal (J.S.-F.); Pirogov Russian National Research Medical University, Moscow, Russia (N.S.); Universitair Ziekenhuis Brussel, Belgium (R.B.); Santa Casa de São Paulo, Medical School, Brazil (R.J.G.); Department of Neurology, Hospital of the University of Pennsylvania, Philadelphia (S.E.K.); Emergency Department Stroke Unit, Hospital Policlinico Umberto I, Department of Neurology and Psychiatry, 'Sapienza' University, Rome, Italy (A.P.); Department of Neurology, University Hospital Heidelberg, Germany (P.V.); Department of Neurology, Tokyo Women's Medical University, Japan (K.K.); Department of Neurology, Beijing Tiantan Hospital, Capital Medical University, China (Y.W.); Institute of Neuroscience & Psychology, University of Glasgow, Queen Elizabeth University Hospital, United Kingdom (K.M.); and Academic Medical Center, Amsterdam, the Netherlands (J.M.C.).</nlm:affiliation><orgName type="university">Université McMaster</orgName><country>Canada</country><placeName><settlement type="city">Hamilton (Ontario)</settlement><region type="state">Ontario</region></placeName></affiliation></author><author><name sortKey="Wang, Yongjun" sort="Wang, Yongjun" uniqKey="Wang Y" first="Yongjun" last="Wang">Yongjun Wang</name><affiliation wicri:level="4"><nlm:affiliation>From the Population Health Research Institute, McMaster University, Hamilton Health Sciences, Ontario, Canada (K.S.P., J.B., B.S., M.G., S.J.C., R.G.H.); Department of Cardiovascular Sciences, University of Leuven, Belgium (T.V.); Bayer-Pharma AG, Wuppertal, Germany (H.M.); Instituto Nacional de Neurologia y Neurocirugia, Mexico D.F., Mexico (M.A.B.); University of Galway, Ireland (M.J.O.); Institute for Neurological Research, Fundacion para la Lucha contra las Enfermedades Neurologicas de la Infancia (FLENI), Buenos Aires, Argentina (M.G.-S.); School of Medicine and Pharmacology, University of Western Australia, Sir Charles Gairdner Hospital, Perth, Australia (G.J.H.); Department of Neurology, Seoul National University Hospital, Korea (B.-W.Y.); Medical City Hospital, Manila, Philippines (A.R.); Department of Neurology, Bichat Hospital, Paris, France (P.L.); Centro Hospitalar e Universitário de Coimbra, Portugal (J.S.-F.); Pirogov Russian National Research Medical University, Moscow, Russia (N.S.); Universitair Ziekenhuis Brussel, Belgium (R.B.); Santa Casa de São Paulo, Medical School, Brazil (R.J.G.); Department of Neurology, Hospital of the University of Pennsylvania, Philadelphia (S.E.K.); Emergency Department Stroke Unit, Hospital Policlinico Umberto I, Department of Neurology and Psychiatry, 'Sapienza' University, Rome, Italy (A.P.); Department of Neurology, University Hospital Heidelberg, Germany (P.V.); Department of Neurology, Tokyo Women's Medical University, Japan (K.K.); Department of Neurology, Beijing Tiantan Hospital, Capital Medical University, China (Y.W.); Institute of Neuroscience & Psychology, University of Glasgow, Queen Elizabeth University Hospital, United Kingdom (K.M.); and Academic Medical Center, Amsterdam, the Netherlands (J.M.C.).</nlm:affiliation><orgName type="university">Université McMaster</orgName><country>Canada</country><placeName><settlement type="city">Hamilton (Ontario)</settlement><region type="state">Ontario</region></placeName></affiliation></author><author><name sortKey="Muir, Keith" sort="Muir, Keith" uniqKey="Muir K" first="Keith" last="Muir">Keith Muir</name><affiliation wicri:level="4"><nlm:affiliation>From the Population Health Research Institute, McMaster University, Hamilton Health Sciences, Ontario, Canada (K.S.P., J.B., B.S., M.G., S.J.C., R.G.H.); Department of Cardiovascular Sciences, University of Leuven, Belgium (T.V.); Bayer-Pharma AG, Wuppertal, Germany (H.M.); Instituto Nacional de Neurologia y Neurocirugia, Mexico D.F., Mexico (M.A.B.); University of Galway, Ireland (M.J.O.); Institute for Neurological Research, Fundacion para la Lucha contra las Enfermedades Neurologicas de la Infancia (FLENI), Buenos Aires, Argentina (M.G.-S.); School of Medicine and Pharmacology, University of Western Australia, Sir Charles Gairdner Hospital, Perth, Australia (G.J.H.); Department of Neurology, Seoul National University Hospital, Korea (B.-W.Y.); Medical City Hospital, Manila, Philippines (A.R.); Department of Neurology, Bichat Hospital, Paris, France (P.L.); Centro Hospitalar e Universitário de Coimbra, Portugal (J.S.-F.); Pirogov Russian National Research Medical University, Moscow, Russia (N.S.); Universitair Ziekenhuis Brussel, Belgium (R.B.); Santa Casa de São Paulo, Medical School, Brazil (R.J.G.); Department of Neurology, Hospital of the University of Pennsylvania, Philadelphia (S.E.K.); Emergency Department Stroke Unit, Hospital Policlinico Umberto I, Department of Neurology and Psychiatry, 'Sapienza' University, Rome, Italy (A.P.); Department of Neurology, University Hospital Heidelberg, Germany (P.V.); Department of Neurology, Tokyo Women's Medical University, Japan (K.K.); Department of Neurology, Beijing Tiantan Hospital, Capital Medical University, China (Y.W.); Institute of Neuroscience & Psychology, University of Glasgow, Queen Elizabeth University Hospital, United Kingdom (K.M.); and Academic Medical Center, Amsterdam, the Netherlands (J.M.C.).</nlm:affiliation><orgName type="university">Université McMaster</orgName><country>Canada</country><placeName><settlement type="city">Hamilton (Ontario)</settlement><region type="state">Ontario</region></placeName></affiliation></author><author><name sortKey="Coutinho, Jonathan M" sort="Coutinho, Jonathan M" uniqKey="Coutinho J" first="Jonathan M" last="Coutinho">Jonathan M. Coutinho</name><affiliation wicri:level="4"><nlm:affiliation>From the Population Health Research Institute, McMaster University, Hamilton Health Sciences, Ontario, Canada (K.S.P., J.B., B.S., M.G., S.J.C., R.G.H.); Department of Cardiovascular Sciences, University of Leuven, Belgium (T.V.); Bayer-Pharma AG, Wuppertal, Germany (H.M.); Instituto Nacional de Neurologia y Neurocirugia, Mexico D.F., Mexico (M.A.B.); University of Galway, Ireland (M.J.O.); Institute for Neurological Research, Fundacion para la Lucha contra las Enfermedades Neurologicas de la Infancia (FLENI), Buenos Aires, Argentina (M.G.-S.); School of Medicine and Pharmacology, University of Western Australia, Sir Charles Gairdner Hospital, Perth, Australia (G.J.H.); Department of Neurology, Seoul National University Hospital, Korea (B.-W.Y.); Medical City Hospital, Manila, Philippines (A.R.); Department of Neurology, Bichat Hospital, Paris, France (P.L.); Centro Hospitalar e Universitário de Coimbra, Portugal (J.S.-F.); Pirogov Russian National Research Medical University, Moscow, Russia (N.S.); Universitair Ziekenhuis Brussel, Belgium (R.B.); Santa Casa de São Paulo, Medical School, Brazil (R.J.G.); Department of Neurology, Hospital of the University of Pennsylvania, Philadelphia (S.E.K.); Emergency Department Stroke Unit, Hospital Policlinico Umberto I, Department of Neurology and Psychiatry, 'Sapienza' University, Rome, Italy (A.P.); Department of Neurology, University Hospital Heidelberg, Germany (P.V.); Department of Neurology, Tokyo Women's Medical University, Japan (K.K.); Department of Neurology, Beijing Tiantan Hospital, Capital Medical University, China (Y.W.); Institute of Neuroscience & Psychology, University of Glasgow, Queen Elizabeth University Hospital, United Kingdom (K.M.); and Academic Medical Center, Amsterdam, the Netherlands (J.M.C.).</nlm:affiliation><orgName type="university">Université McMaster</orgName><country>Canada</country><placeName><settlement type="city">Hamilton (Ontario)</settlement><region type="state">Ontario</region></placeName></affiliation></author><author><name sortKey="Connolly, Stuart J" sort="Connolly, Stuart J" uniqKey="Connolly S" first="Stuart J" last="Connolly">Stuart J. Connolly</name><affiliation wicri:level="4"><nlm:affiliation>From the Population Health Research Institute, McMaster University, Hamilton Health Sciences, Ontario, Canada (K.S.P., J.B., B.S., M.G., S.J.C., R.G.H.); Department of Cardiovascular Sciences, University of Leuven, Belgium (T.V.); Bayer-Pharma AG, Wuppertal, Germany (H.M.); Instituto Nacional de Neurologia y Neurocirugia, Mexico D.F., Mexico (M.A.B.); University of Galway, Ireland (M.J.O.); Institute for Neurological Research, Fundacion para la Lucha contra las Enfermedades Neurologicas de la Infancia (FLENI), Buenos Aires, Argentina (M.G.-S.); School of Medicine and Pharmacology, University of Western Australia, Sir Charles Gairdner Hospital, Perth, Australia (G.J.H.); Department of Neurology, Seoul National University Hospital, Korea (B.-W.Y.); Medical City Hospital, Manila, Philippines (A.R.); Department of Neurology, Bichat Hospital, Paris, France (P.L.); Centro Hospitalar e Universitário de Coimbra, Portugal (J.S.-F.); Pirogov Russian National Research Medical University, Moscow, Russia (N.S.); Universitair Ziekenhuis Brussel, Belgium (R.B.); Santa Casa de São Paulo, Medical School, Brazil (R.J.G.); Department of Neurology, Hospital of the University of Pennsylvania, Philadelphia (S.E.K.); Emergency Department Stroke Unit, Hospital Policlinico Umberto I, Department of Neurology and Psychiatry, 'Sapienza' University, Rome, Italy (A.P.); Department of Neurology, University Hospital Heidelberg, Germany (P.V.); Department of Neurology, Tokyo Women's Medical University, Japan (K.K.); Department of Neurology, Beijing Tiantan Hospital, Capital Medical University, China (Y.W.); Institute of Neuroscience & Psychology, University of Glasgow, Queen Elizabeth University Hospital, United Kingdom (K.M.); and Academic Medical Center, Amsterdam, the Netherlands (J.M.C.).</nlm:affiliation><orgName type="university">Université McMaster</orgName><country>Canada</country><placeName><settlement type="city">Hamilton (Ontario)</settlement><region type="state">Ontario</region></placeName></affiliation></author><author><name sortKey="Hart, Robert G" sort="Hart, Robert G" uniqKey="Hart R" first="Robert G" last="Hart">Robert G. Hart</name><affiliation wicri:level="4"><nlm:affiliation>From the Population Health Research Institute, McMaster University, Hamilton Health Sciences, Ontario, Canada (K.S.P., J.B., B.S., M.G., S.J.C., R.G.H.); Department of Cardiovascular Sciences, University of Leuven, Belgium (T.V.); Bayer-Pharma AG, Wuppertal, Germany (H.M.); Instituto Nacional de Neurologia y Neurocirugia, Mexico D.F., Mexico (M.A.B.); University of Galway, Ireland (M.J.O.); Institute for Neurological Research, Fundacion para la Lucha contra las Enfermedades Neurologicas de la Infancia (FLENI), Buenos Aires, Argentina (M.G.-S.); School of Medicine and Pharmacology, University of Western Australia, Sir Charles Gairdner Hospital, Perth, Australia (G.J.H.); Department of Neurology, Seoul National University Hospital, Korea (B.-W.Y.); Medical City Hospital, Manila, Philippines (A.R.); Department of Neurology, Bichat Hospital, Paris, France (P.L.); Centro Hospitalar e Universitário de Coimbra, Portugal (J.S.-F.); Pirogov Russian National Research Medical University, Moscow, Russia (N.S.); Universitair Ziekenhuis Brussel, Belgium (R.B.); Santa Casa de São Paulo, Medical School, Brazil (R.J.G.); Department of Neurology, Hospital of the University of Pennsylvania, Philadelphia (S.E.K.); Emergency Department Stroke Unit, Hospital Policlinico Umberto I, Department of Neurology and Psychiatry, 'Sapienza' University, Rome, Italy (A.P.); Department of Neurology, University Hospital Heidelberg, Germany (P.V.); Department of Neurology, Tokyo Women's Medical University, Japan (K.K.); Department of Neurology, Beijing Tiantan Hospital, Capital Medical University, China (Y.W.); Institute of Neuroscience & Psychology, University of Glasgow, Queen Elizabeth University Hospital, United Kingdom (K.M.); and Academic Medical Center, Amsterdam, the Netherlands (J.M.C.).</nlm:affiliation><orgName type="university">Université McMaster</orgName><country>Canada</country><placeName><settlement type="city">Hamilton (Ontario)</settlement><region type="state">Ontario</region></placeName></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="2016">2016</date><idno type="RBID">pubmed:27507860</idno><idno type="pmid">27507860</idno><idno type="doi">10.1161/STROKEAHA.116.013378</idno><idno type="wicri:Area/PubMed/Corpus">001887</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Corpus" wicri:corpus="PubMed">001887</idno><idno type="wicri:Area/PubMed/Curation">001864</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Curation">001864</idno><idno type="wicri:Area/PubMed/Checkpoint">001864</idno><idno type="wicri:explorRef" wicri:stream="Checkpoint" wicri:step="PubMed">001864</idno><idno type="wicri:Area/Ncbi/Merge">003967</idno><idno type="wicri:Area/Ncbi/Curation">003967</idno><idno type="wicri:Area/Ncbi/Checkpoint">003967</idno><idno type="wicri:Area/Main/Merge">001E12</idno><idno type="wicri:Area/Main/Curation">001E15</idno><idno type="wicri:Area/Main/Exploration">001E15</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">Global Survey of the Frequency of Atrial Fibrillation-Associated Stroke: Embolic Stroke of Undetermined Source Global Registry.</title><author><name sortKey="Perera, Kanjana S" sort="Perera, Kanjana S" uniqKey="Perera K" first="Kanjana S" last="Perera">Kanjana S. Perera</name><affiliation wicri:level="1"><nlm:affiliation>From the Population Health Research Institute, McMaster University, Hamilton Health Sciences, Ontario, Canada (K.S.P., J.B., B.S., M.G., S.J.C., R.G.H.); Department of Cardiovascular Sciences, University of Leuven, Belgium (T.V.); Bayer-Pharma AG, Wuppertal, Germany (H.M.); Instituto Nacional de Neurologia y Neurocirugia, Mexico D.F., Mexico (M.A.B.); University of Galway, Ireland (M.J.O.); Institute for Neurological Research, Fundacion para la Lucha contra las Enfermedades Neurologicas de la Infancia (FLENI), Buenos Aires, Argentina (M.G.-S.); School of Medicine and Pharmacology, University of Western Australia, Sir Charles Gairdner Hospital, Perth, Australia (G.J.H.); Department of Neurology, Seoul National University Hospital, Korea (B.-W.Y.); Medical City Hospital, Manila, Philippines (A.R.); Department of Neurology, Bichat Hospital, Paris, France (P.L.); Centro Hospitalar e Universitário de Coimbra, Portugal (J.S.-F.); Pirogov Russian National Research Medical University, Moscow, Russia (N.S.); Universitair Ziekenhuis Brussel, Belgium (R.B.); Santa Casa de São Paulo, Medical School, Brazil (R.J.G.); Department of Neurology, Hospital of the University of Pennsylvania, Philadelphia (S.E.K.); Emergency Department Stroke Unit, Hospital Policlinico Umberto I, Department of Neurology and Psychiatry, 'Sapienza' University, Rome, Italy (A.P.); Department of Neurology, University Hospital Heidelberg, Germany (P.V.); Department of Neurology, Tokyo Women's Medical University, Japan (K.K.); Department of Neurology, Beijing Tiantan Hospital, Capital Medical University, China (Y.W.); Institute of Neuroscience & Psychology, University of Glasgow, Queen Elizabeth University Hospital, United Kingdom (K.M.); and Academic Medical Center, Amsterdam, the Netherlands (J.M.C.). kanjana.perera@phri.ca.</nlm:affiliation><country wicri:rule="url">Canada</country></affiliation></author><author><name sortKey="Vanassche, Thomas" sort="Vanassche, Thomas" uniqKey="Vanassche T" first="Thomas" last="Vanassche">Thomas Vanassche</name><affiliation wicri:level="4"><nlm:affiliation>From the Population Health Research Institute, McMaster University, Hamilton Health Sciences, Ontario, Canada (K.S.P., J.B., B.S., M.G., S.J.C., R.G.H.); Department of Cardiovascular Sciences, University of Leuven, Belgium (T.V.); Bayer-Pharma AG, Wuppertal, Germany (H.M.); Instituto Nacional de Neurologia y Neurocirugia, Mexico D.F., Mexico (M.A.B.); University of Galway, Ireland (M.J.O.); Institute for Neurological Research, Fundacion para la Lucha contra las Enfermedades Neurologicas de la Infancia (FLENI), Buenos Aires, Argentina (M.G.-S.); School of Medicine and Pharmacology, University of Western Australia, Sir Charles Gairdner Hospital, Perth, Australia (G.J.H.); Department of Neurology, Seoul National University Hospital, Korea (B.-W.Y.); Medical City Hospital, Manila, Philippines (A.R.); Department of Neurology, Bichat Hospital, Paris, France (P.L.); Centro Hospitalar e Universitário de Coimbra, Portugal (J.S.-F.); Pirogov Russian National Research Medical University, Moscow, Russia (N.S.); Universitair Ziekenhuis Brussel, Belgium (R.B.); Santa Casa de São Paulo, Medical School, Brazil (R.J.G.); Department of Neurology, Hospital of the University of Pennsylvania, Philadelphia (S.E.K.); Emergency Department Stroke Unit, Hospital Policlinico Umberto I, Department of Neurology and Psychiatry, 'Sapienza' University, Rome, Italy (A.P.); Department of Neurology, University Hospital Heidelberg, Germany (P.V.); Department of Neurology, Tokyo Women's Medical University, Japan (K.K.); Department of Neurology, Beijing Tiantan Hospital, Capital Medical University, China (Y.W.); Institute of Neuroscience & Psychology, University of Glasgow, Queen Elizabeth University Hospital, United Kingdom (K.M.); and Academic Medical Center, Amsterdam, the Netherlands (J.M.C.).</nlm:affiliation><orgName type="university">Université McMaster</orgName><country>Canada</country><placeName><settlement type="city">Hamilton (Ontario)</settlement><region type="state">Ontario</region></placeName></affiliation></author><author><name sortKey="Bosch, Jackie" sort="Bosch, Jackie" uniqKey="Bosch J" first="Jackie" last="Bosch">Jackie Bosch</name><affiliation wicri:level="4"><nlm:affiliation>From the Population Health Research Institute, McMaster University, Hamilton Health Sciences, Ontario, Canada (K.S.P., J.B., B.S., M.G., S.J.C., R.G.H.); Department of Cardiovascular Sciences, University of Leuven, Belgium (T.V.); Bayer-Pharma AG, Wuppertal, Germany (H.M.); Instituto Nacional de Neurologia y Neurocirugia, Mexico D.F., Mexico (M.A.B.); University of Galway, Ireland (M.J.O.); Institute for Neurological Research, Fundacion para la Lucha contra las Enfermedades Neurologicas de la Infancia (FLENI), Buenos Aires, Argentina (M.G.-S.); School of Medicine and Pharmacology, University of Western Australia, Sir Charles Gairdner Hospital, Perth, Australia (G.J.H.); Department of Neurology, Seoul National University Hospital, Korea (B.-W.Y.); Medical City Hospital, Manila, Philippines (A.R.); Department of Neurology, Bichat Hospital, Paris, France (P.L.); Centro Hospitalar e Universitário de Coimbra, Portugal (J.S.-F.); Pirogov Russian National Research Medical University, Moscow, Russia (N.S.); Universitair Ziekenhuis Brussel, Belgium (R.B.); Santa Casa de São Paulo, Medical School, Brazil (R.J.G.); Department of Neurology, Hospital of the University of Pennsylvania, Philadelphia (S.E.K.); Emergency Department Stroke Unit, Hospital Policlinico Umberto I, Department of Neurology and Psychiatry, 'Sapienza' University, Rome, Italy (A.P.); Department of Neurology, University Hospital Heidelberg, Germany (P.V.); Department of Neurology, Tokyo Women's Medical University, Japan (K.K.); Department of Neurology, Beijing Tiantan Hospital, Capital Medical University, China (Y.W.); Institute of Neuroscience & Psychology, University of Glasgow, Queen Elizabeth University Hospital, United Kingdom (K.M.); and Academic Medical Center, Amsterdam, the Netherlands (J.M.C.).</nlm:affiliation><orgName type="university">Université McMaster</orgName><country>Canada</country><placeName><settlement type="city">Hamilton (Ontario)</settlement><region type="state">Ontario</region></placeName></affiliation></author><author><name sortKey="Swaminathan, Balakumar" sort="Swaminathan, Balakumar" uniqKey="Swaminathan B" first="Balakumar" last="Swaminathan">Balakumar Swaminathan</name><affiliation wicri:level="4"><nlm:affiliation>From the Population Health Research Institute, McMaster University, Hamilton Health Sciences, Ontario, Canada (K.S.P., J.B., B.S., M.G., S.J.C., R.G.H.); Department of Cardiovascular Sciences, University of Leuven, Belgium (T.V.); Bayer-Pharma AG, Wuppertal, Germany (H.M.); Instituto Nacional de Neurologia y Neurocirugia, Mexico D.F., Mexico (M.A.B.); University of Galway, Ireland (M.J.O.); Institute for Neurological Research, Fundacion para la Lucha contra las Enfermedades Neurologicas de la Infancia (FLENI), Buenos Aires, Argentina (M.G.-S.); School of Medicine and Pharmacology, University of Western Australia, Sir Charles Gairdner Hospital, Perth, Australia (G.J.H.); Department of Neurology, Seoul National University Hospital, Korea (B.-W.Y.); Medical City Hospital, Manila, Philippines (A.R.); Department of Neurology, Bichat Hospital, Paris, France (P.L.); Centro Hospitalar e Universitário de Coimbra, Portugal (J.S.-F.); Pirogov Russian National Research Medical University, Moscow, Russia (N.S.); Universitair Ziekenhuis Brussel, Belgium (R.B.); Santa Casa de São Paulo, Medical School, Brazil (R.J.G.); Department of Neurology, Hospital of the University of Pennsylvania, Philadelphia (S.E.K.); Emergency Department Stroke Unit, Hospital Policlinico Umberto I, Department of Neurology and Psychiatry, 'Sapienza' University, Rome, Italy (A.P.); Department of Neurology, University Hospital Heidelberg, Germany (P.V.); Department of Neurology, Tokyo Women's Medical University, Japan (K.K.); Department of Neurology, Beijing Tiantan Hospital, Capital Medical University, China (Y.W.); Institute of Neuroscience & Psychology, University of Glasgow, Queen Elizabeth University Hospital, United Kingdom (K.M.); and Academic Medical Center, Amsterdam, the Netherlands (J.M.C.).</nlm:affiliation><orgName type="university">Université McMaster</orgName><country>Canada</country><placeName><settlement type="city">Hamilton (Ontario)</settlement><region type="state">Ontario</region></placeName></affiliation></author><author><name sortKey="Mundl, Hardi" sort="Mundl, Hardi" uniqKey="Mundl H" first="Hardi" last="Mundl">Hardi Mundl</name><affiliation wicri:level="4"><nlm:affiliation>From the Population Health Research Institute, McMaster University, Hamilton Health Sciences, Ontario, Canada (K.S.P., J.B., B.S., M.G., S.J.C., R.G.H.); Department of Cardiovascular Sciences, University of Leuven, Belgium (T.V.); Bayer-Pharma AG, Wuppertal, Germany (H.M.); Instituto Nacional de Neurologia y Neurocirugia, Mexico D.F., Mexico (M.A.B.); University of Galway, Ireland (M.J.O.); Institute for Neurological Research, Fundacion para la Lucha contra las Enfermedades Neurologicas de la Infancia (FLENI), Buenos Aires, Argentina (M.G.-S.); School of Medicine and Pharmacology, University of Western Australia, Sir Charles Gairdner Hospital, Perth, Australia (G.J.H.); Department of Neurology, Seoul National University Hospital, Korea (B.-W.Y.); Medical City Hospital, Manila, Philippines (A.R.); Department of Neurology, Bichat Hospital, Paris, France (P.L.); Centro Hospitalar e Universitário de Coimbra, Portugal (J.S.-F.); Pirogov Russian National Research Medical University, Moscow, Russia (N.S.); Universitair Ziekenhuis Brussel, Belgium (R.B.); Santa Casa de São Paulo, Medical School, Brazil (R.J.G.); Department of Neurology, Hospital of the University of Pennsylvania, Philadelphia (S.E.K.); Emergency Department Stroke Unit, Hospital Policlinico Umberto I, Department of Neurology and Psychiatry, 'Sapienza' University, Rome, Italy (A.P.); Department of Neurology, University Hospital Heidelberg, Germany (P.V.); Department of Neurology, Tokyo Women's Medical University, Japan (K.K.); Department of Neurology, Beijing Tiantan Hospital, Capital Medical University, China (Y.W.); Institute of Neuroscience & Psychology, University of Glasgow, Queen Elizabeth University Hospital, United Kingdom (K.M.); and Academic Medical Center, Amsterdam, the Netherlands (J.M.C.).</nlm:affiliation><orgName type="university">Université McMaster</orgName><country>Canada</country><placeName><settlement type="city">Hamilton (Ontario)</settlement><region type="state">Ontario</region></placeName></affiliation></author><author><name sortKey="Giruparajah, Mohana" sort="Giruparajah, Mohana" uniqKey="Giruparajah M" first="Mohana" last="Giruparajah">Mohana Giruparajah</name><affiliation wicri:level="4"><nlm:affiliation>From the Population Health Research Institute, McMaster University, Hamilton Health Sciences, Ontario, Canada (K.S.P., J.B., B.S., M.G., S.J.C., R.G.H.); Department of Cardiovascular Sciences, University of Leuven, Belgium (T.V.); Bayer-Pharma AG, Wuppertal, Germany (H.M.); Instituto Nacional de Neurologia y Neurocirugia, Mexico D.F., Mexico (M.A.B.); University of Galway, Ireland (M.J.O.); Institute for Neurological Research, Fundacion para la Lucha contra las Enfermedades Neurologicas de la Infancia (FLENI), Buenos Aires, Argentina (M.G.-S.); School of Medicine and Pharmacology, University of Western Australia, Sir Charles Gairdner Hospital, Perth, Australia (G.J.H.); Department of Neurology, Seoul National University Hospital, Korea (B.-W.Y.); Medical City Hospital, Manila, Philippines (A.R.); Department of Neurology, Bichat Hospital, Paris, France (P.L.); Centro Hospitalar e Universitário de Coimbra, Portugal (J.S.-F.); Pirogov Russian National Research Medical University, Moscow, Russia (N.S.); Universitair Ziekenhuis Brussel, Belgium (R.B.); Santa Casa de São Paulo, Medical School, Brazil (R.J.G.); Department of Neurology, Hospital of the University of Pennsylvania, Philadelphia (S.E.K.); Emergency Department Stroke Unit, Hospital Policlinico Umberto I, Department of Neurology and Psychiatry, 'Sapienza' University, Rome, Italy (A.P.); Department of Neurology, University Hospital Heidelberg, Germany (P.V.); Department of Neurology, Tokyo Women's Medical University, Japan (K.K.); Department of Neurology, Beijing Tiantan Hospital, Capital Medical University, China (Y.W.); Institute of Neuroscience & Psychology, University of Glasgow, Queen Elizabeth University Hospital, United Kingdom (K.M.); and Academic Medical Center, Amsterdam, the Netherlands (J.M.C.).</nlm:affiliation><orgName type="university">Université McMaster</orgName><country>Canada</country><placeName><settlement type="city">Hamilton (Ontario)</settlement><region type="state">Ontario</region></placeName></affiliation></author><author><name sortKey="Barboza, Miguel A" sort="Barboza, Miguel A" uniqKey="Barboza M" first="Miguel A" last="Barboza">Miguel A. Barboza</name><affiliation wicri:level="4"><nlm:affiliation>From the Population Health Research Institute, McMaster University, Hamilton Health Sciences, Ontario, Canada (K.S.P., J.B., B.S., M.G., S.J.C., R.G.H.); Department of Cardiovascular Sciences, University of Leuven, Belgium (T.V.); Bayer-Pharma AG, Wuppertal, Germany (H.M.); Instituto Nacional de Neurologia y Neurocirugia, Mexico D.F., Mexico (M.A.B.); University of Galway, Ireland (M.J.O.); Institute for Neurological Research, Fundacion para la Lucha contra las Enfermedades Neurologicas de la Infancia (FLENI), Buenos Aires, Argentina (M.G.-S.); School of Medicine and Pharmacology, University of Western Australia, Sir Charles Gairdner Hospital, Perth, Australia (G.J.H.); Department of Neurology, Seoul National University Hospital, Korea (B.-W.Y.); Medical City Hospital, Manila, Philippines (A.R.); Department of Neurology, Bichat Hospital, Paris, France (P.L.); Centro Hospitalar e Universitário de Coimbra, Portugal (J.S.-F.); Pirogov Russian National Research Medical University, Moscow, Russia (N.S.); Universitair Ziekenhuis Brussel, Belgium (R.B.); Santa Casa de São Paulo, Medical School, Brazil (R.J.G.); Department of Neurology, Hospital of the University of Pennsylvania, Philadelphia (S.E.K.); Emergency Department Stroke Unit, Hospital Policlinico Umberto I, Department of Neurology and Psychiatry, 'Sapienza' University, Rome, Italy (A.P.); Department of Neurology, University Hospital Heidelberg, Germany (P.V.); Department of Neurology, Tokyo Women's Medical University, Japan (K.K.); Department of Neurology, Beijing Tiantan Hospital, Capital Medical University, China (Y.W.); Institute of Neuroscience & Psychology, University of Glasgow, Queen Elizabeth University Hospital, United Kingdom (K.M.); and Academic Medical Center, Amsterdam, the Netherlands (J.M.C.).</nlm:affiliation><orgName type="university">Université McMaster</orgName><country>Canada</country><placeName><settlement type="city">Hamilton (Ontario)</settlement><region type="state">Ontario</region></placeName></affiliation></author><author><name sortKey="O Donnell, Martin J" sort="O Donnell, Martin J" uniqKey="O Donnell M" first="Martin J" last="O'Donnell">Martin J. O'Donnell</name><affiliation wicri:level="4"><nlm:affiliation>From the Population Health Research Institute, McMaster University, Hamilton Health Sciences, Ontario, Canada (K.S.P., J.B., B.S., M.G., S.J.C., R.G.H.); Department of Cardiovascular Sciences, University of Leuven, Belgium (T.V.); Bayer-Pharma AG, Wuppertal, Germany (H.M.); Instituto Nacional de Neurologia y Neurocirugia, Mexico D.F., Mexico (M.A.B.); University of Galway, Ireland (M.J.O.); Institute for Neurological Research, Fundacion para la Lucha contra las Enfermedades Neurologicas de la Infancia (FLENI), Buenos Aires, Argentina (M.G.-S.); School of Medicine and Pharmacology, University of Western Australia, Sir Charles Gairdner Hospital, Perth, Australia (G.J.H.); Department of Neurology, Seoul National University Hospital, Korea (B.-W.Y.); Medical City Hospital, Manila, Philippines (A.R.); Department of Neurology, Bichat Hospital, Paris, France (P.L.); Centro Hospitalar e Universitário de Coimbra, Portugal (J.S.-F.); Pirogov Russian National Research Medical University, Moscow, Russia (N.S.); Universitair Ziekenhuis Brussel, Belgium (R.B.); Santa Casa de São Paulo, Medical School, Brazil (R.J.G.); Department of Neurology, Hospital of the University of Pennsylvania, Philadelphia (S.E.K.); Emergency Department Stroke Unit, Hospital Policlinico Umberto I, Department of Neurology and Psychiatry, 'Sapienza' University, Rome, Italy (A.P.); Department of Neurology, University Hospital Heidelberg, Germany (P.V.); Department of Neurology, Tokyo Women's Medical University, Japan (K.K.); Department of Neurology, Beijing Tiantan Hospital, Capital Medical University, China (Y.W.); Institute of Neuroscience & Psychology, University of Glasgow, Queen Elizabeth University Hospital, United Kingdom (K.M.); and Academic Medical Center, Amsterdam, the Netherlands (J.M.C.).</nlm:affiliation><orgName type="university">Université McMaster</orgName><country>Canada</country><placeName><settlement type="city">Hamilton (Ontario)</settlement><region type="state">Ontario</region></placeName></affiliation></author><author><name sortKey="Gomez Schneider, Maia" sort="Gomez Schneider, Maia" uniqKey="Gomez Schneider M" first="Maia" last="Gomez-Schneider">Maia Gomez-Schneider</name><affiliation wicri:level="4"><nlm:affiliation>From the Population Health Research Institute, McMaster University, Hamilton Health Sciences, Ontario, Canada (K.S.P., J.B., B.S., M.G., S.J.C., R.G.H.); Department of Cardiovascular Sciences, University of Leuven, Belgium (T.V.); Bayer-Pharma AG, Wuppertal, Germany (H.M.); Instituto Nacional de Neurologia y Neurocirugia, Mexico D.F., Mexico (M.A.B.); University of Galway, Ireland (M.J.O.); Institute for Neurological Research, Fundacion para la Lucha contra las Enfermedades Neurologicas de la Infancia (FLENI), Buenos Aires, Argentina (M.G.-S.); School of Medicine and Pharmacology, University of Western Australia, Sir Charles Gairdner Hospital, Perth, Australia (G.J.H.); Department of Neurology, Seoul National University Hospital, Korea (B.-W.Y.); Medical City Hospital, Manila, Philippines (A.R.); Department of Neurology, Bichat Hospital, Paris, France (P.L.); Centro Hospitalar e Universitário de Coimbra, Portugal (J.S.-F.); Pirogov Russian National Research Medical University, Moscow, Russia (N.S.); Universitair Ziekenhuis Brussel, Belgium (R.B.); Santa Casa de São Paulo, Medical School, Brazil (R.J.G.); Department of Neurology, Hospital of the University of Pennsylvania, Philadelphia (S.E.K.); Emergency Department Stroke Unit, Hospital Policlinico Umberto I, Department of Neurology and Psychiatry, 'Sapienza' University, Rome, Italy (A.P.); Department of Neurology, University Hospital Heidelberg, Germany (P.V.); Department of Neurology, Tokyo Women's Medical University, Japan (K.K.); Department of Neurology, Beijing Tiantan Hospital, Capital Medical University, China (Y.W.); Institute of Neuroscience & Psychology, University of Glasgow, Queen Elizabeth University Hospital, United Kingdom (K.M.); and Academic Medical Center, Amsterdam, the Netherlands (J.M.C.).</nlm:affiliation><orgName type="university">Université McMaster</orgName><country>Canada</country><placeName><settlement type="city">Hamilton (Ontario)</settlement><region type="state">Ontario</region></placeName></affiliation></author><author><name sortKey="Hankey, Graeme J" sort="Hankey, Graeme J" uniqKey="Hankey G" first="Graeme J" last="Hankey">Graeme J. Hankey</name><affiliation wicri:level="4"><nlm:affiliation>From the Population Health Research Institute, McMaster University, Hamilton Health Sciences, Ontario, Canada (K.S.P., J.B., B.S., M.G., S.J.C., R.G.H.); Department of Cardiovascular Sciences, University of Leuven, Belgium (T.V.); Bayer-Pharma AG, Wuppertal, Germany (H.M.); Instituto Nacional de Neurologia y Neurocirugia, Mexico D.F., Mexico (M.A.B.); University of Galway, Ireland (M.J.O.); Institute for Neurological Research, Fundacion para la Lucha contra las Enfermedades Neurologicas de la Infancia (FLENI), Buenos Aires, Argentina (M.G.-S.); School of Medicine and Pharmacology, University of Western Australia, Sir Charles Gairdner Hospital, Perth, Australia (G.J.H.); Department of Neurology, Seoul National University Hospital, Korea (B.-W.Y.); Medical City Hospital, Manila, Philippines (A.R.); Department of Neurology, Bichat Hospital, Paris, France (P.L.); Centro Hospitalar e Universitário de Coimbra, Portugal (J.S.-F.); Pirogov Russian National Research Medical University, Moscow, Russia (N.S.); Universitair Ziekenhuis Brussel, Belgium (R.B.); Santa Casa de São Paulo, Medical School, Brazil (R.J.G.); Department of Neurology, Hospital of the University of Pennsylvania, Philadelphia (S.E.K.); Emergency Department Stroke Unit, Hospital Policlinico Umberto I, Department of Neurology and Psychiatry, 'Sapienza' University, Rome, Italy (A.P.); Department of Neurology, University Hospital Heidelberg, Germany (P.V.); Department of Neurology, Tokyo Women's Medical University, Japan (K.K.); Department of Neurology, Beijing Tiantan Hospital, Capital Medical University, China (Y.W.); Institute of Neuroscience & Psychology, University of Glasgow, Queen Elizabeth University Hospital, United Kingdom (K.M.); and Academic Medical Center, Amsterdam, the Netherlands (J.M.C.).</nlm:affiliation><orgName type="university">Université McMaster</orgName><country>Canada</country><placeName><settlement type="city">Hamilton (Ontario)</settlement><region type="state">Ontario</region></placeName></affiliation></author><author><name sortKey="Yoon, Byung Woo" sort="Yoon, Byung Woo" uniqKey="Yoon B" first="Byung-Woo" last="Yoon">Byung-Woo Yoon</name><affiliation wicri:level="4"><nlm:affiliation>From the Population Health Research Institute, McMaster University, Hamilton Health Sciences, Ontario, Canada (K.S.P., J.B., B.S., M.G., S.J.C., R.G.H.); Department of Cardiovascular Sciences, University of Leuven, Belgium (T.V.); Bayer-Pharma AG, Wuppertal, Germany (H.M.); Instituto Nacional de Neurologia y Neurocirugia, Mexico D.F., Mexico (M.A.B.); University of Galway, Ireland (M.J.O.); Institute for Neurological Research, Fundacion para la Lucha contra las Enfermedades Neurologicas de la Infancia (FLENI), Buenos Aires, Argentina (M.G.-S.); School of Medicine and Pharmacology, University of Western Australia, Sir Charles Gairdner Hospital, Perth, Australia (G.J.H.); Department of Neurology, Seoul National University Hospital, Korea (B.-W.Y.); Medical City Hospital, Manila, Philippines (A.R.); Department of Neurology, Bichat Hospital, Paris, France (P.L.); Centro Hospitalar e Universitário de Coimbra, Portugal (J.S.-F.); Pirogov Russian National Research Medical University, Moscow, Russia (N.S.); Universitair Ziekenhuis Brussel, Belgium (R.B.); Santa Casa de São Paulo, Medical School, Brazil (R.J.G.); Department of Neurology, Hospital of the University of Pennsylvania, Philadelphia (S.E.K.); Emergency Department Stroke Unit, Hospital Policlinico Umberto I, Department of Neurology and Psychiatry, 'Sapienza' University, Rome, Italy (A.P.); Department of Neurology, University Hospital Heidelberg, Germany (P.V.); Department of Neurology, Tokyo Women's Medical University, Japan (K.K.); Department of Neurology, Beijing Tiantan Hospital, Capital Medical University, China (Y.W.); Institute of Neuroscience & Psychology, University of Glasgow, Queen Elizabeth University Hospital, United Kingdom (K.M.); and Academic Medical Center, Amsterdam, the Netherlands (J.M.C.).</nlm:affiliation><orgName type="university">Université McMaster</orgName><country>Canada</country><placeName><settlement type="city">Hamilton (Ontario)</settlement><region type="state">Ontario</region></placeName></affiliation></author><author><name sortKey="Roxas, Artemio" sort="Roxas, Artemio" uniqKey="Roxas A" first="Artemio" last="Roxas">Artemio Roxas</name><affiliation wicri:level="4"><nlm:affiliation>From the Population Health Research Institute, McMaster University, Hamilton Health Sciences, Ontario, Canada (K.S.P., J.B., B.S., M.G., S.J.C., R.G.H.); Department of Cardiovascular Sciences, University of Leuven, Belgium (T.V.); Bayer-Pharma AG, Wuppertal, Germany (H.M.); Instituto Nacional de Neurologia y Neurocirugia, Mexico D.F., Mexico (M.A.B.); University of Galway, Ireland (M.J.O.); Institute for Neurological Research, Fundacion para la Lucha contra las Enfermedades Neurologicas de la Infancia (FLENI), Buenos Aires, Argentina (M.G.-S.); School of Medicine and Pharmacology, University of Western Australia, Sir Charles Gairdner Hospital, Perth, Australia (G.J.H.); Department of Neurology, Seoul National University Hospital, Korea (B.-W.Y.); Medical City Hospital, Manila, Philippines (A.R.); Department of Neurology, Bichat Hospital, Paris, France (P.L.); Centro Hospitalar e Universitário de Coimbra, Portugal (J.S.-F.); Pirogov Russian National Research Medical University, Moscow, Russia (N.S.); Universitair Ziekenhuis Brussel, Belgium (R.B.); Santa Casa de São Paulo, Medical School, Brazil (R.J.G.); Department of Neurology, Hospital of the University of Pennsylvania, Philadelphia (S.E.K.); Emergency Department Stroke Unit, Hospital Policlinico Umberto I, Department of Neurology and Psychiatry, 'Sapienza' University, Rome, Italy (A.P.); Department of Neurology, University Hospital Heidelberg, Germany (P.V.); Department of Neurology, Tokyo Women's Medical University, Japan (K.K.); Department of Neurology, Beijing Tiantan Hospital, Capital Medical University, China (Y.W.); Institute of Neuroscience & Psychology, University of Glasgow, Queen Elizabeth University Hospital, United Kingdom (K.M.); and Academic Medical Center, Amsterdam, the Netherlands (J.M.C.).</nlm:affiliation><orgName type="university">Université McMaster</orgName><country>Canada</country><placeName><settlement type="city">Hamilton (Ontario)</settlement><region type="state">Ontario</region></placeName></affiliation></author><author><name sortKey="Lavallee, Philippa" sort="Lavallee, Philippa" uniqKey="Lavallee P" first="Philippa" last="Lavallee">Philippa Lavallee</name><affiliation wicri:level="4"><nlm:affiliation>From the Population Health Research Institute, McMaster University, Hamilton Health Sciences, Ontario, Canada (K.S.P., J.B., B.S., M.G., S.J.C., R.G.H.); Department of Cardiovascular Sciences, University of Leuven, Belgium (T.V.); Bayer-Pharma AG, Wuppertal, Germany (H.M.); Instituto Nacional de Neurologia y Neurocirugia, Mexico D.F., Mexico (M.A.B.); University of Galway, Ireland (M.J.O.); Institute for Neurological Research, Fundacion para la Lucha contra las Enfermedades Neurologicas de la Infancia (FLENI), Buenos Aires, Argentina (M.G.-S.); School of Medicine and Pharmacology, University of Western Australia, Sir Charles Gairdner Hospital, Perth, Australia (G.J.H.); Department of Neurology, Seoul National University Hospital, Korea (B.-W.Y.); Medical City Hospital, Manila, Philippines (A.R.); Department of Neurology, Bichat Hospital, Paris, France (P.L.); Centro Hospitalar e Universitário de Coimbra, Portugal (J.S.-F.); Pirogov Russian National Research Medical University, Moscow, Russia (N.S.); Universitair Ziekenhuis Brussel, Belgium (R.B.); Santa Casa de São Paulo, Medical School, Brazil (R.J.G.); Department of Neurology, Hospital of the University of Pennsylvania, Philadelphia (S.E.K.); Emergency Department Stroke Unit, Hospital Policlinico Umberto I, Department of Neurology and Psychiatry, 'Sapienza' University, Rome, Italy (A.P.); Department of Neurology, University Hospital Heidelberg, Germany (P.V.); Department of Neurology, Tokyo Women's Medical University, Japan (K.K.); Department of Neurology, Beijing Tiantan Hospital, Capital Medical University, China (Y.W.); Institute of Neuroscience & Psychology, University of Glasgow, Queen Elizabeth University Hospital, United Kingdom (K.M.); and Academic Medical Center, Amsterdam, the Netherlands (J.M.C.).</nlm:affiliation><orgName type="university">Université McMaster</orgName><country>Canada</country><placeName><settlement type="city">Hamilton (Ontario)</settlement><region type="state">Ontario</region></placeName></affiliation></author><author><name sortKey="Sargento Freitas, Joao" sort="Sargento Freitas, Joao" uniqKey="Sargento Freitas J" first="Joao" last="Sargento-Freitas">Joao Sargento-Freitas</name><affiliation wicri:level="4"><nlm:affiliation>From the Population Health Research Institute, McMaster University, Hamilton Health Sciences, Ontario, Canada (K.S.P., J.B., B.S., M.G., S.J.C., R.G.H.); Department of Cardiovascular Sciences, University of Leuven, Belgium (T.V.); Bayer-Pharma AG, Wuppertal, Germany (H.M.); Instituto Nacional de Neurologia y Neurocirugia, Mexico D.F., Mexico (M.A.B.); University of Galway, Ireland (M.J.O.); Institute for Neurological Research, Fundacion para la Lucha contra las Enfermedades Neurologicas de la Infancia (FLENI), Buenos Aires, Argentina (M.G.-S.); School of Medicine and Pharmacology, University of Western Australia, Sir Charles Gairdner Hospital, Perth, Australia (G.J.H.); Department of Neurology, Seoul National University Hospital, Korea (B.-W.Y.); Medical City Hospital, Manila, Philippines (A.R.); Department of Neurology, Bichat Hospital, Paris, France (P.L.); Centro Hospitalar e Universitário de Coimbra, Portugal (J.S.-F.); Pirogov Russian National Research Medical University, Moscow, Russia (N.S.); Universitair Ziekenhuis Brussel, Belgium (R.B.); Santa Casa de São Paulo, Medical School, Brazil (R.J.G.); Department of Neurology, Hospital of the University of Pennsylvania, Philadelphia (S.E.K.); Emergency Department Stroke Unit, Hospital Policlinico Umberto I, Department of Neurology and Psychiatry, 'Sapienza' University, Rome, Italy (A.P.); Department of Neurology, University Hospital Heidelberg, Germany (P.V.); Department of Neurology, Tokyo Women's Medical University, Japan (K.K.); Department of Neurology, Beijing Tiantan Hospital, Capital Medical University, China (Y.W.); Institute of Neuroscience & Psychology, University of Glasgow, Queen Elizabeth University Hospital, United Kingdom (K.M.); and Academic Medical Center, Amsterdam, the Netherlands (J.M.C.).</nlm:affiliation><orgName type="university">Université McMaster</orgName><country>Canada</country><placeName><settlement type="city">Hamilton (Ontario)</settlement><region type="state">Ontario</region></placeName></affiliation></author><author><name sortKey="Shamalov, Nikolay" sort="Shamalov, Nikolay" uniqKey="Shamalov N" first="Nikolay" last="Shamalov">Nikolay Shamalov</name><affiliation wicri:level="4"><nlm:affiliation>From the Population Health Research Institute, McMaster University, Hamilton Health Sciences, Ontario, Canada (K.S.P., J.B., B.S., M.G., S.J.C., R.G.H.); Department of Cardiovascular Sciences, University of Leuven, Belgium (T.V.); Bayer-Pharma AG, Wuppertal, Germany (H.M.); Instituto Nacional de Neurologia y Neurocirugia, Mexico D.F., Mexico (M.A.B.); University of Galway, Ireland (M.J.O.); Institute for Neurological Research, Fundacion para la Lucha contra las Enfermedades Neurologicas de la Infancia (FLENI), Buenos Aires, Argentina (M.G.-S.); School of Medicine and Pharmacology, University of Western Australia, Sir Charles Gairdner Hospital, Perth, Australia (G.J.H.); Department of Neurology, Seoul National University Hospital, Korea (B.-W.Y.); Medical City Hospital, Manila, Philippines (A.R.); Department of Neurology, Bichat Hospital, Paris, France (P.L.); Centro Hospitalar e Universitário de Coimbra, Portugal (J.S.-F.); Pirogov Russian National Research Medical University, Moscow, Russia (N.S.); Universitair Ziekenhuis Brussel, Belgium (R.B.); Santa Casa de São Paulo, Medical School, Brazil (R.J.G.); Department of Neurology, Hospital of the University of Pennsylvania, Philadelphia (S.E.K.); Emergency Department Stroke Unit, Hospital Policlinico Umberto I, Department of Neurology and Psychiatry, 'Sapienza' University, Rome, Italy (A.P.); Department of Neurology, University Hospital Heidelberg, Germany (P.V.); Department of Neurology, Tokyo Women's Medical University, Japan (K.K.); Department of Neurology, Beijing Tiantan Hospital, Capital Medical University, China (Y.W.); Institute of Neuroscience & Psychology, University of Glasgow, Queen Elizabeth University Hospital, United Kingdom (K.M.); and Academic Medical Center, Amsterdam, the Netherlands (J.M.C.).</nlm:affiliation><orgName type="university">Université McMaster</orgName><country>Canada</country><placeName><settlement type="city">Hamilton (Ontario)</settlement><region type="state">Ontario</region></placeName></affiliation></author><author><name sortKey="Brouns, Raf" sort="Brouns, Raf" uniqKey="Brouns R" first="Raf" last="Brouns">Raf Brouns</name><affiliation wicri:level="4"><nlm:affiliation>From the Population Health Research Institute, McMaster University, Hamilton Health Sciences, Ontario, Canada (K.S.P., J.B., B.S., M.G., S.J.C., R.G.H.); Department of Cardiovascular Sciences, University of Leuven, Belgium (T.V.); Bayer-Pharma AG, Wuppertal, Germany (H.M.); Instituto Nacional de Neurologia y Neurocirugia, Mexico D.F., Mexico (M.A.B.); University of Galway, Ireland (M.J.O.); Institute for Neurological Research, Fundacion para la Lucha contra las Enfermedades Neurologicas de la Infancia (FLENI), Buenos Aires, Argentina (M.G.-S.); School of Medicine and Pharmacology, University of Western Australia, Sir Charles Gairdner Hospital, Perth, Australia (G.J.H.); Department of Neurology, Seoul National University Hospital, Korea (B.-W.Y.); Medical City Hospital, Manila, Philippines (A.R.); Department of Neurology, Bichat Hospital, Paris, France (P.L.); Centro Hospitalar e Universitário de Coimbra, Portugal (J.S.-F.); Pirogov Russian National Research Medical University, Moscow, Russia (N.S.); Universitair Ziekenhuis Brussel, Belgium (R.B.); Santa Casa de São Paulo, Medical School, Brazil (R.J.G.); Department of Neurology, Hospital of the University of Pennsylvania, Philadelphia (S.E.K.); Emergency Department Stroke Unit, Hospital Policlinico Umberto I, Department of Neurology and Psychiatry, 'Sapienza' University, Rome, Italy (A.P.); Department of Neurology, University Hospital Heidelberg, Germany (P.V.); Department of Neurology, Tokyo Women's Medical University, Japan (K.K.); Department of Neurology, Beijing Tiantan Hospital, Capital Medical University, China (Y.W.); Institute of Neuroscience & Psychology, University of Glasgow, Queen Elizabeth University Hospital, United Kingdom (K.M.); and Academic Medical Center, Amsterdam, the Netherlands (J.M.C.).</nlm:affiliation><orgName type="university">Université McMaster</orgName><country>Canada</country><placeName><settlement type="city">Hamilton (Ontario)</settlement><region type="state">Ontario</region></placeName></affiliation></author><author><name sortKey="Gagliardi, Rubens J" sort="Gagliardi, Rubens J" uniqKey="Gagliardi R" first="Rubens J" last="Gagliardi">Rubens J. Gagliardi</name><affiliation wicri:level="4"><nlm:affiliation>From the Population Health Research Institute, McMaster University, Hamilton Health Sciences, Ontario, Canada (K.S.P., J.B., B.S., M.G., S.J.C., R.G.H.); Department of Cardiovascular Sciences, University of Leuven, Belgium (T.V.); Bayer-Pharma AG, Wuppertal, Germany (H.M.); Instituto Nacional de Neurologia y Neurocirugia, Mexico D.F., Mexico (M.A.B.); University of Galway, Ireland (M.J.O.); Institute for Neurological Research, Fundacion para la Lucha contra las Enfermedades Neurologicas de la Infancia (FLENI), Buenos Aires, Argentina (M.G.-S.); School of Medicine and Pharmacology, University of Western Australia, Sir Charles Gairdner Hospital, Perth, Australia (G.J.H.); Department of Neurology, Seoul National University Hospital, Korea (B.-W.Y.); Medical City Hospital, Manila, Philippines (A.R.); Department of Neurology, Bichat Hospital, Paris, France (P.L.); Centro Hospitalar e Universitário de Coimbra, Portugal (J.S.-F.); Pirogov Russian National Research Medical University, Moscow, Russia (N.S.); Universitair Ziekenhuis Brussel, Belgium (R.B.); Santa Casa de São Paulo, Medical School, Brazil (R.J.G.); Department of Neurology, Hospital of the University of Pennsylvania, Philadelphia (S.E.K.); Emergency Department Stroke Unit, Hospital Policlinico Umberto I, Department of Neurology and Psychiatry, 'Sapienza' University, Rome, Italy (A.P.); Department of Neurology, University Hospital Heidelberg, Germany (P.V.); Department of Neurology, Tokyo Women's Medical University, Japan (K.K.); Department of Neurology, Beijing Tiantan Hospital, Capital Medical University, China (Y.W.); Institute of Neuroscience & Psychology, University of Glasgow, Queen Elizabeth University Hospital, United Kingdom (K.M.); and Academic Medical Center, Amsterdam, the Netherlands (J.M.C.).</nlm:affiliation><orgName type="university">Université McMaster</orgName><country>Canada</country><placeName><settlement type="city">Hamilton (Ontario)</settlement><region type="state">Ontario</region></placeName></affiliation></author><author><name sortKey="Kasner, Scott E" sort="Kasner, Scott E" uniqKey="Kasner S" first="Scott E" last="Kasner">Scott E. Kasner</name><affiliation wicri:level="4"><nlm:affiliation>From the Population Health Research Institute, McMaster University, Hamilton Health Sciences, Ontario, Canada (K.S.P., J.B., B.S., M.G., S.J.C., R.G.H.); Department of Cardiovascular Sciences, University of Leuven, Belgium (T.V.); Bayer-Pharma AG, Wuppertal, Germany (H.M.); Instituto Nacional de Neurologia y Neurocirugia, Mexico D.F., Mexico (M.A.B.); University of Galway, Ireland (M.J.O.); Institute for Neurological Research, Fundacion para la Lucha contra las Enfermedades Neurologicas de la Infancia (FLENI), Buenos Aires, Argentina (M.G.-S.); School of Medicine and Pharmacology, University of Western Australia, Sir Charles Gairdner Hospital, Perth, Australia (G.J.H.); Department of Neurology, Seoul National University Hospital, Korea (B.-W.Y.); Medical City Hospital, Manila, Philippines (A.R.); Department of Neurology, Bichat Hospital, Paris, France (P.L.); Centro Hospitalar e Universitário de Coimbra, Portugal (J.S.-F.); Pirogov Russian National Research Medical University, Moscow, Russia (N.S.); Universitair Ziekenhuis Brussel, Belgium (R.B.); Santa Casa de São Paulo, Medical School, Brazil (R.J.G.); Department of Neurology, Hospital of the University of Pennsylvania, Philadelphia (S.E.K.); Emergency Department Stroke Unit, Hospital Policlinico Umberto I, Department of Neurology and Psychiatry, 'Sapienza' University, Rome, Italy (A.P.); Department of Neurology, University Hospital Heidelberg, Germany (P.V.); Department of Neurology, Tokyo Women's Medical University, Japan (K.K.); Department of Neurology, Beijing Tiantan Hospital, Capital Medical University, China (Y.W.); Institute of Neuroscience & Psychology, University of Glasgow, Queen Elizabeth University Hospital, United Kingdom (K.M.); and Academic Medical Center, Amsterdam, the Netherlands (J.M.C.).</nlm:affiliation><orgName type="university">Université McMaster</orgName><country>Canada</country><placeName><settlement type="city">Hamilton (Ontario)</settlement><region type="state">Ontario</region></placeName></affiliation></author><author><name sortKey="Pieroni, Alessio" sort="Pieroni, Alessio" uniqKey="Pieroni A" first="Alessio" last="Pieroni">Alessio Pieroni</name><affiliation wicri:level="4"><nlm:affiliation>From the Population Health Research Institute, McMaster University, Hamilton Health Sciences, Ontario, Canada (K.S.P., J.B., B.S., M.G., S.J.C., R.G.H.); Department of Cardiovascular Sciences, University of Leuven, Belgium (T.V.); Bayer-Pharma AG, Wuppertal, Germany (H.M.); Instituto Nacional de Neurologia y Neurocirugia, Mexico D.F., Mexico (M.A.B.); University of Galway, Ireland (M.J.O.); Institute for Neurological Research, Fundacion para la Lucha contra las Enfermedades Neurologicas de la Infancia (FLENI), Buenos Aires, Argentina (M.G.-S.); School of Medicine and Pharmacology, University of Western Australia, Sir Charles Gairdner Hospital, Perth, Australia (G.J.H.); Department of Neurology, Seoul National University Hospital, Korea (B.-W.Y.); Medical City Hospital, Manila, Philippines (A.R.); Department of Neurology, Bichat Hospital, Paris, France (P.L.); Centro Hospitalar e Universitário de Coimbra, Portugal (J.S.-F.); Pirogov Russian National Research Medical University, Moscow, Russia (N.S.); Universitair Ziekenhuis Brussel, Belgium (R.B.); Santa Casa de São Paulo, Medical School, Brazil (R.J.G.); Department of Neurology, Hospital of the University of Pennsylvania, Philadelphia (S.E.K.); Emergency Department Stroke Unit, Hospital Policlinico Umberto I, Department of Neurology and Psychiatry, 'Sapienza' University, Rome, Italy (A.P.); Department of Neurology, University Hospital Heidelberg, Germany (P.V.); Department of Neurology, Tokyo Women's Medical University, Japan (K.K.); Department of Neurology, Beijing Tiantan Hospital, Capital Medical University, China (Y.W.); Institute of Neuroscience & Psychology, University of Glasgow, Queen Elizabeth University Hospital, United Kingdom (K.M.); and Academic Medical Center, Amsterdam, the Netherlands (J.M.C.).</nlm:affiliation><orgName type="university">Université McMaster</orgName><country>Canada</country><placeName><settlement type="city">Hamilton (Ontario)</settlement><region type="state">Ontario</region></placeName></affiliation></author><author><name sortKey="Vermehren, Philipp" sort="Vermehren, Philipp" uniqKey="Vermehren P" first="Philipp" last="Vermehren">Philipp Vermehren</name><affiliation wicri:level="4"><nlm:affiliation>From the Population Health Research Institute, McMaster University, Hamilton Health Sciences, Ontario, Canada (K.S.P., J.B., B.S., M.G., S.J.C., R.G.H.); Department of Cardiovascular Sciences, University of Leuven, Belgium (T.V.); Bayer-Pharma AG, Wuppertal, Germany (H.M.); Instituto Nacional de Neurologia y Neurocirugia, Mexico D.F., Mexico (M.A.B.); University of Galway, Ireland (M.J.O.); Institute for Neurological Research, Fundacion para la Lucha contra las Enfermedades Neurologicas de la Infancia (FLENI), Buenos Aires, Argentina (M.G.-S.); School of Medicine and Pharmacology, University of Western Australia, Sir Charles Gairdner Hospital, Perth, Australia (G.J.H.); Department of Neurology, Seoul National University Hospital, Korea (B.-W.Y.); Medical City Hospital, Manila, Philippines (A.R.); Department of Neurology, Bichat Hospital, Paris, France (P.L.); Centro Hospitalar e Universitário de Coimbra, Portugal (J.S.-F.); Pirogov Russian National Research Medical University, Moscow, Russia (N.S.); Universitair Ziekenhuis Brussel, Belgium (R.B.); Santa Casa de São Paulo, Medical School, Brazil (R.J.G.); Department of Neurology, Hospital of the University of Pennsylvania, Philadelphia (S.E.K.); Emergency Department Stroke Unit, Hospital Policlinico Umberto I, Department of Neurology and Psychiatry, 'Sapienza' University, Rome, Italy (A.P.); Department of Neurology, University Hospital Heidelberg, Germany (P.V.); Department of Neurology, Tokyo Women's Medical University, Japan (K.K.); Department of Neurology, Beijing Tiantan Hospital, Capital Medical University, China (Y.W.); Institute of Neuroscience & Psychology, University of Glasgow, Queen Elizabeth University Hospital, United Kingdom (K.M.); and Academic Medical Center, Amsterdam, the Netherlands (J.M.C.).</nlm:affiliation><orgName type="university">Université McMaster</orgName><country>Canada</country><placeName><settlement type="city">Hamilton (Ontario)</settlement><region type="state">Ontario</region></placeName></affiliation></author><author><name sortKey="Kitagawa, Kazuo" sort="Kitagawa, Kazuo" uniqKey="Kitagawa K" first="Kazuo" last="Kitagawa">Kazuo Kitagawa</name><affiliation wicri:level="4"><nlm:affiliation>From the Population Health Research Institute, McMaster University, Hamilton Health Sciences, Ontario, Canada (K.S.P., J.B., B.S., M.G., S.J.C., R.G.H.); Department of Cardiovascular Sciences, University of Leuven, Belgium (T.V.); Bayer-Pharma AG, Wuppertal, Germany (H.M.); Instituto Nacional de Neurologia y Neurocirugia, Mexico D.F., Mexico (M.A.B.); University of Galway, Ireland (M.J.O.); Institute for Neurological Research, Fundacion para la Lucha contra las Enfermedades Neurologicas de la Infancia (FLENI), Buenos Aires, Argentina (M.G.-S.); School of Medicine and Pharmacology, University of Western Australia, Sir Charles Gairdner Hospital, Perth, Australia (G.J.H.); Department of Neurology, Seoul National University Hospital, Korea (B.-W.Y.); Medical City Hospital, Manila, Philippines (A.R.); Department of Neurology, Bichat Hospital, Paris, France (P.L.); Centro Hospitalar e Universitário de Coimbra, Portugal (J.S.-F.); Pirogov Russian National Research Medical University, Moscow, Russia (N.S.); Universitair Ziekenhuis Brussel, Belgium (R.B.); Santa Casa de São Paulo, Medical School, Brazil (R.J.G.); Department of Neurology, Hospital of the University of Pennsylvania, Philadelphia (S.E.K.); Emergency Department Stroke Unit, Hospital Policlinico Umberto I, Department of Neurology and Psychiatry, 'Sapienza' University, Rome, Italy (A.P.); Department of Neurology, University Hospital Heidelberg, Germany (P.V.); Department of Neurology, Tokyo Women's Medical University, Japan (K.K.); Department of Neurology, Beijing Tiantan Hospital, Capital Medical University, China (Y.W.); Institute of Neuroscience & Psychology, University of Glasgow, Queen Elizabeth University Hospital, United Kingdom (K.M.); and Academic Medical Center, Amsterdam, the Netherlands (J.M.C.).</nlm:affiliation><orgName type="university">Université McMaster</orgName><country>Canada</country><placeName><settlement type="city">Hamilton (Ontario)</settlement><region type="state">Ontario</region></placeName></affiliation></author><author><name sortKey="Wang, Yongjun" sort="Wang, Yongjun" uniqKey="Wang Y" first="Yongjun" last="Wang">Yongjun Wang</name><affiliation wicri:level="4"><nlm:affiliation>From the Population Health Research Institute, McMaster University, Hamilton Health Sciences, Ontario, Canada (K.S.P., J.B., B.S., M.G., S.J.C., R.G.H.); Department of Cardiovascular Sciences, University of Leuven, Belgium (T.V.); Bayer-Pharma AG, Wuppertal, Germany (H.M.); Instituto Nacional de Neurologia y Neurocirugia, Mexico D.F., Mexico (M.A.B.); University of Galway, Ireland (M.J.O.); Institute for Neurological Research, Fundacion para la Lucha contra las Enfermedades Neurologicas de la Infancia (FLENI), Buenos Aires, Argentina (M.G.-S.); School of Medicine and Pharmacology, University of Western Australia, Sir Charles Gairdner Hospital, Perth, Australia (G.J.H.); Department of Neurology, Seoul National University Hospital, Korea (B.-W.Y.); Medical City Hospital, Manila, Philippines (A.R.); Department of Neurology, Bichat Hospital, Paris, France (P.L.); Centro Hospitalar e Universitário de Coimbra, Portugal (J.S.-F.); Pirogov Russian National Research Medical University, Moscow, Russia (N.S.); Universitair Ziekenhuis Brussel, Belgium (R.B.); Santa Casa de São Paulo, Medical School, Brazil (R.J.G.); Department of Neurology, Hospital of the University of Pennsylvania, Philadelphia (S.E.K.); Emergency Department Stroke Unit, Hospital Policlinico Umberto I, Department of Neurology and Psychiatry, 'Sapienza' University, Rome, Italy (A.P.); Department of Neurology, University Hospital Heidelberg, Germany (P.V.); Department of Neurology, Tokyo Women's Medical University, Japan (K.K.); Department of Neurology, Beijing Tiantan Hospital, Capital Medical University, China (Y.W.); Institute of Neuroscience & Psychology, University of Glasgow, Queen Elizabeth University Hospital, United Kingdom (K.M.); and Academic Medical Center, Amsterdam, the Netherlands (J.M.C.).</nlm:affiliation><orgName type="university">Université McMaster</orgName><country>Canada</country><placeName><settlement type="city">Hamilton (Ontario)</settlement><region type="state">Ontario</region></placeName></affiliation></author><author><name sortKey="Muir, Keith" sort="Muir, Keith" uniqKey="Muir K" first="Keith" last="Muir">Keith Muir</name><affiliation wicri:level="4"><nlm:affiliation>From the Population Health Research Institute, McMaster University, Hamilton Health Sciences, Ontario, Canada (K.S.P., J.B., B.S., M.G., S.J.C., R.G.H.); Department of Cardiovascular Sciences, University of Leuven, Belgium (T.V.); Bayer-Pharma AG, Wuppertal, Germany (H.M.); Instituto Nacional de Neurologia y Neurocirugia, Mexico D.F., Mexico (M.A.B.); University of Galway, Ireland (M.J.O.); Institute for Neurological Research, Fundacion para la Lucha contra las Enfermedades Neurologicas de la Infancia (FLENI), Buenos Aires, Argentina (M.G.-S.); School of Medicine and Pharmacology, University of Western Australia, Sir Charles Gairdner Hospital, Perth, Australia (G.J.H.); Department of Neurology, Seoul National University Hospital, Korea (B.-W.Y.); Medical City Hospital, Manila, Philippines (A.R.); Department of Neurology, Bichat Hospital, Paris, France (P.L.); Centro Hospitalar e Universitário de Coimbra, Portugal (J.S.-F.); Pirogov Russian National Research Medical University, Moscow, Russia (N.S.); Universitair Ziekenhuis Brussel, Belgium (R.B.); Santa Casa de São Paulo, Medical School, Brazil (R.J.G.); Department of Neurology, Hospital of the University of Pennsylvania, Philadelphia (S.E.K.); Emergency Department Stroke Unit, Hospital Policlinico Umberto I, Department of Neurology and Psychiatry, 'Sapienza' University, Rome, Italy (A.P.); Department of Neurology, University Hospital Heidelberg, Germany (P.V.); Department of Neurology, Tokyo Women's Medical University, Japan (K.K.); Department of Neurology, Beijing Tiantan Hospital, Capital Medical University, China (Y.W.); Institute of Neuroscience & Psychology, University of Glasgow, Queen Elizabeth University Hospital, United Kingdom (K.M.); and Academic Medical Center, Amsterdam, the Netherlands (J.M.C.).</nlm:affiliation><orgName type="university">Université McMaster</orgName><country>Canada</country><placeName><settlement type="city">Hamilton (Ontario)</settlement><region type="state">Ontario</region></placeName></affiliation></author><author><name sortKey="Coutinho, Jonathan M" sort="Coutinho, Jonathan M" uniqKey="Coutinho J" first="Jonathan M" last="Coutinho">Jonathan M. Coutinho</name><affiliation wicri:level="4"><nlm:affiliation>From the Population Health Research Institute, McMaster University, Hamilton Health Sciences, Ontario, Canada (K.S.P., J.B., B.S., M.G., S.J.C., R.G.H.); Department of Cardiovascular Sciences, University of Leuven, Belgium (T.V.); Bayer-Pharma AG, Wuppertal, Germany (H.M.); Instituto Nacional de Neurologia y Neurocirugia, Mexico D.F., Mexico (M.A.B.); University of Galway, Ireland (M.J.O.); Institute for Neurological Research, Fundacion para la Lucha contra las Enfermedades Neurologicas de la Infancia (FLENI), Buenos Aires, Argentina (M.G.-S.); School of Medicine and Pharmacology, University of Western Australia, Sir Charles Gairdner Hospital, Perth, Australia (G.J.H.); Department of Neurology, Seoul National University Hospital, Korea (B.-W.Y.); Medical City Hospital, Manila, Philippines (A.R.); Department of Neurology, Bichat Hospital, Paris, France (P.L.); Centro Hospitalar e Universitário de Coimbra, Portugal (J.S.-F.); Pirogov Russian National Research Medical University, Moscow, Russia (N.S.); Universitair Ziekenhuis Brussel, Belgium (R.B.); Santa Casa de São Paulo, Medical School, Brazil (R.J.G.); Department of Neurology, Hospital of the University of Pennsylvania, Philadelphia (S.E.K.); Emergency Department Stroke Unit, Hospital Policlinico Umberto I, Department of Neurology and Psychiatry, 'Sapienza' University, Rome, Italy (A.P.); Department of Neurology, University Hospital Heidelberg, Germany (P.V.); Department of Neurology, Tokyo Women's Medical University, Japan (K.K.); Department of Neurology, Beijing Tiantan Hospital, Capital Medical University, China (Y.W.); Institute of Neuroscience & Psychology, University of Glasgow, Queen Elizabeth University Hospital, United Kingdom (K.M.); and Academic Medical Center, Amsterdam, the Netherlands (J.M.C.).</nlm:affiliation><orgName type="university">Université McMaster</orgName><country>Canada</country><placeName><settlement type="city">Hamilton (Ontario)</settlement><region type="state">Ontario</region></placeName></affiliation></author><author><name sortKey="Connolly, Stuart J" sort="Connolly, Stuart J" uniqKey="Connolly S" first="Stuart J" last="Connolly">Stuart J. Connolly</name><affiliation wicri:level="4"><nlm:affiliation>From the Population Health Research Institute, McMaster University, Hamilton Health Sciences, Ontario, Canada (K.S.P., J.B., B.S., M.G., S.J.C., R.G.H.); Department of Cardiovascular Sciences, University of Leuven, Belgium (T.V.); Bayer-Pharma AG, Wuppertal, Germany (H.M.); Instituto Nacional de Neurologia y Neurocirugia, Mexico D.F., Mexico (M.A.B.); University of Galway, Ireland (M.J.O.); Institute for Neurological Research, Fundacion para la Lucha contra las Enfermedades Neurologicas de la Infancia (FLENI), Buenos Aires, Argentina (M.G.-S.); School of Medicine and Pharmacology, University of Western Australia, Sir Charles Gairdner Hospital, Perth, Australia (G.J.H.); Department of Neurology, Seoul National University Hospital, Korea (B.-W.Y.); Medical City Hospital, Manila, Philippines (A.R.); Department of Neurology, Bichat Hospital, Paris, France (P.L.); Centro Hospitalar e Universitário de Coimbra, Portugal (J.S.-F.); Pirogov Russian National Research Medical University, Moscow, Russia (N.S.); Universitair Ziekenhuis Brussel, Belgium (R.B.); Santa Casa de São Paulo, Medical School, Brazil (R.J.G.); Department of Neurology, Hospital of the University of Pennsylvania, Philadelphia (S.E.K.); Emergency Department Stroke Unit, Hospital Policlinico Umberto I, Department of Neurology and Psychiatry, 'Sapienza' University, Rome, Italy (A.P.); Department of Neurology, University Hospital Heidelberg, Germany (P.V.); Department of Neurology, Tokyo Women's Medical University, Japan (K.K.); Department of Neurology, Beijing Tiantan Hospital, Capital Medical University, China (Y.W.); Institute of Neuroscience & Psychology, University of Glasgow, Queen Elizabeth University Hospital, United Kingdom (K.M.); and Academic Medical Center, Amsterdam, the Netherlands (J.M.C.).</nlm:affiliation><orgName type="university">Université McMaster</orgName><country>Canada</country><placeName><settlement type="city">Hamilton (Ontario)</settlement><region type="state">Ontario</region></placeName></affiliation></author><author><name sortKey="Hart, Robert G" sort="Hart, Robert G" uniqKey="Hart R" first="Robert G" last="Hart">Robert G. Hart</name><affiliation wicri:level="4"><nlm:affiliation>From the Population Health Research Institute, McMaster University, Hamilton Health Sciences, Ontario, Canada (K.S.P., J.B., B.S., M.G., S.J.C., R.G.H.); Department of Cardiovascular Sciences, University of Leuven, Belgium (T.V.); Bayer-Pharma AG, Wuppertal, Germany (H.M.); Instituto Nacional de Neurologia y Neurocirugia, Mexico D.F., Mexico (M.A.B.); University of Galway, Ireland (M.J.O.); Institute for Neurological Research, Fundacion para la Lucha contra las Enfermedades Neurologicas de la Infancia (FLENI), Buenos Aires, Argentina (M.G.-S.); School of Medicine and Pharmacology, University of Western Australia, Sir Charles Gairdner Hospital, Perth, Australia (G.J.H.); Department of Neurology, Seoul National University Hospital, Korea (B.-W.Y.); Medical City Hospital, Manila, Philippines (A.R.); Department of Neurology, Bichat Hospital, Paris, France (P.L.); Centro Hospitalar e Universitário de Coimbra, Portugal (J.S.-F.); Pirogov Russian National Research Medical University, Moscow, Russia (N.S.); Universitair Ziekenhuis Brussel, Belgium (R.B.); Santa Casa de São Paulo, Medical School, Brazil (R.J.G.); Department of Neurology, Hospital of the University of Pennsylvania, Philadelphia (S.E.K.); Emergency Department Stroke Unit, Hospital Policlinico Umberto I, Department of Neurology and Psychiatry, 'Sapienza' University, Rome, Italy (A.P.); Department of Neurology, University Hospital Heidelberg, Germany (P.V.); Department of Neurology, Tokyo Women's Medical University, Japan (K.K.); Department of Neurology, Beijing Tiantan Hospital, Capital Medical University, China (Y.W.); Institute of Neuroscience & Psychology, University of Glasgow, Queen Elizabeth University Hospital, United Kingdom (K.M.); and Academic Medical Center, Amsterdam, the Netherlands (J.M.C.).</nlm:affiliation><orgName type="university">Université McMaster</orgName><country>Canada</country><placeName><settlement type="city">Hamilton (Ontario)</settlement><region type="state">Ontario</region></placeName></affiliation></author></analytic><series><title level="j">Stroke</title><idno type="eISSN">1524-4628</idno><imprint><date when="2016" type="published">2016</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Age Factors</term><term>Aged</term><term>Atrial Fibrillation (complications)</term><term>Brain Ischemia (epidemiology)</term><term>Brain Ischemia (etiology)</term><term>Brain Ischemia (mortality)</term><term>Electrocardiography</term><term>Female</term><term>Humans</term><term>Incidence</term><term>Intracranial Embolism (epidemiology)</term><term>Intracranial Embolism (etiology)</term><term>Intracranial Embolism (mortality)</term><term>Ischemic Attack, Transient (epidemiology)</term><term>Ischemic Attack, Transient (etiology)</term><term>Ischemic Attack, Transient (mortality)</term><term>Male</term><term>Middle Aged</term><term>Registries</term><term>Sex Factors</term><term>Stroke (epidemiology)</term><term>Stroke (etiology)</term><term>Stroke (mortality)</term><term>Survival Rate</term></keywords><keywords scheme="KwdFr" xml:lang="fr"><term>Accident ischémique transitoire (mortalité)</term><term>Accident ischémique transitoire (épidémiologie)</term><term>Accident ischémique transitoire (étiologie)</term><term>Accident vasculaire cérébral (mortalité)</term><term>Accident vasculaire cérébral (épidémiologie)</term><term>Accident vasculaire cérébral (étiologie)</term><term>Adulte d'âge moyen</term><term>Embolie intracrânienne (mortalité)</term><term>Embolie intracrânienne (épidémiologie)</term><term>Embolie intracrânienne (étiologie)</term><term>Encéphalopathie ischémique (mortalité)</term><term>Encéphalopathie ischémique (épidémiologie)</term><term>Encéphalopathie ischémique (étiologie)</term><term>Enregistrements</term><term>Facteurs de l'âge</term><term>Facteurs sexuels</term><term>Femelle</term><term>Fibrillation auriculaire ()</term><term>Humains</term><term>Incidence</term><term>Mâle</term><term>Sujet âgé</term><term>Taux de survie</term><term>Électrocardiographie</term></keywords><keywords scheme="MESH" qualifier="complications" xml:lang="en"><term>Atrial Fibrillation</term></keywords><keywords scheme="MESH" qualifier="epidemiology" xml:lang="en"><term>Brain Ischemia</term><term>Intracranial Embolism</term><term>Ischemic Attack, Transient</term><term>Stroke</term></keywords><keywords scheme="MESH" qualifier="etiology" xml:lang="en"><term>Brain Ischemia</term><term>Intracranial Embolism</term><term>Ischemic Attack, Transient</term><term>Stroke</term></keywords><keywords scheme="MESH" qualifier="mortality" xml:lang="en"><term>Brain Ischemia</term><term>Intracranial Embolism</term><term>Ischemic Attack, Transient</term><term>Stroke</term></keywords><keywords scheme="MESH" qualifier="mortalité" xml:lang="fr"><term>Accident ischémique transitoire</term><term>Accident vasculaire cérébral</term><term>Embolie intracrânienne</term><term>Encéphalopathie ischémique</term></keywords><keywords scheme="MESH" qualifier="épidémiologie" xml:lang="fr"><term>Accident ischémique transitoire</term><term>Accident vasculaire cérébral</term><term>Embolie intracrânienne</term><term>Encéphalopathie ischémique</term></keywords><keywords scheme="MESH" qualifier="étiologie" xml:lang="fr"><term>Accident ischémique transitoire</term><term>Accident vasculaire cérébral</term><term>Embolie intracrânienne</term><term>Encéphalopathie ischémique</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Age Factors</term><term>Aged</term><term>Electrocardiography</term><term>Female</term><term>Humans</term><term>Incidence</term><term>Male</term><term>Middle Aged</term><term>Registries</term><term>Sex Factors</term><term>Survival Rate</term></keywords><keywords scheme="MESH" xml:lang="fr"><term>Adulte d'âge moyen</term><term>Enregistrements</term><term>Facteurs de l'âge</term><term>Facteurs sexuels</term><term>Femelle</term><term>Fibrillation auriculaire</term><term>Humains</term><term>Incidence</term><term>Mâle</term><term>Sujet âgé</term><term>Taux de survie</term><term>Électrocardiographie</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Atrial fibrillation (AF) is increasingly recognized as the single most important cause of disabling ischemic stroke in the elderly. We undertook an international survey to characterize the frequency of AF-associated stroke, methods of AF detection, and patient features.</div></front></TEI><affiliations><list><country><li>Canada</li></country><region><li>Ontario</li></region><settlement><li>Hamilton (Ontario)</li></settlement><orgName><li>Université McMaster</li></orgName></list><tree><country name="Canada"><noRegion><name sortKey="Perera, Kanjana S" sort="Perera, Kanjana S" uniqKey="Perera K" first="Kanjana S" last="Perera">Kanjana S. Perera</name></noRegion><name sortKey="Barboza, Miguel A" sort="Barboza, Miguel A" uniqKey="Barboza M" first="Miguel A" last="Barboza">Miguel A. Barboza</name><name sortKey="Bosch, Jackie" sort="Bosch, Jackie" uniqKey="Bosch J" first="Jackie" last="Bosch">Jackie Bosch</name><name sortKey="Brouns, Raf" sort="Brouns, Raf" uniqKey="Brouns R" first="Raf" last="Brouns">Raf Brouns</name><name sortKey="Connolly, Stuart J" sort="Connolly, Stuart J" uniqKey="Connolly S" first="Stuart J" last="Connolly">Stuart J. Connolly</name><name sortKey="Coutinho, Jonathan M" sort="Coutinho, Jonathan M" uniqKey="Coutinho J" first="Jonathan M" last="Coutinho">Jonathan M. Coutinho</name><name sortKey="Gagliardi, Rubens J" sort="Gagliardi, Rubens J" uniqKey="Gagliardi R" first="Rubens J" last="Gagliardi">Rubens J. Gagliardi</name><name sortKey="Giruparajah, Mohana" sort="Giruparajah, Mohana" uniqKey="Giruparajah M" first="Mohana" last="Giruparajah">Mohana Giruparajah</name><name sortKey="Gomez Schneider, Maia" sort="Gomez Schneider, Maia" uniqKey="Gomez Schneider M" first="Maia" last="Gomez-Schneider">Maia Gomez-Schneider</name><name sortKey="Hankey, Graeme J" sort="Hankey, Graeme J" uniqKey="Hankey G" first="Graeme J" last="Hankey">Graeme J. Hankey</name><name sortKey="Hart, Robert G" sort="Hart, Robert G" uniqKey="Hart R" first="Robert G" last="Hart">Robert G. Hart</name><name sortKey="Kasner, Scott E" sort="Kasner, Scott E" uniqKey="Kasner S" first="Scott E" last="Kasner">Scott E. Kasner</name><name sortKey="Kitagawa, Kazuo" sort="Kitagawa, Kazuo" uniqKey="Kitagawa K" first="Kazuo" last="Kitagawa">Kazuo Kitagawa</name><name sortKey="Lavallee, Philippa" sort="Lavallee, Philippa" uniqKey="Lavallee P" first="Philippa" last="Lavallee">Philippa Lavallee</name><name sortKey="Muir, Keith" sort="Muir, Keith" uniqKey="Muir K" first="Keith" last="Muir">Keith Muir</name><name sortKey="Mundl, Hardi" sort="Mundl, Hardi" uniqKey="Mundl H" first="Hardi" last="Mundl">Hardi Mundl</name><name sortKey="O Donnell, Martin J" sort="O Donnell, Martin J" uniqKey="O Donnell M" first="Martin J" last="O'Donnell">Martin J. O'Donnell</name><name sortKey="Pieroni, Alessio" sort="Pieroni, Alessio" uniqKey="Pieroni A" first="Alessio" last="Pieroni">Alessio Pieroni</name><name sortKey="Roxas, Artemio" sort="Roxas, Artemio" uniqKey="Roxas A" first="Artemio" last="Roxas">Artemio Roxas</name><name sortKey="Sargento Freitas, Joao" sort="Sargento Freitas, Joao" uniqKey="Sargento Freitas J" first="Joao" last="Sargento-Freitas">Joao Sargento-Freitas</name><name sortKey="Shamalov, Nikolay" sort="Shamalov, Nikolay" uniqKey="Shamalov N" first="Nikolay" last="Shamalov">Nikolay Shamalov</name><name sortKey="Swaminathan, Balakumar" sort="Swaminathan, Balakumar" uniqKey="Swaminathan B" first="Balakumar" last="Swaminathan">Balakumar Swaminathan</name><name sortKey="Vanassche, Thomas" sort="Vanassche, Thomas" uniqKey="Vanassche T" first="Thomas" last="Vanassche">Thomas Vanassche</name><name sortKey="Vermehren, Philipp" sort="Vermehren, Philipp" uniqKey="Vermehren P" first="Philipp" last="Vermehren">Philipp Vermehren</name><name sortKey="Wang, Yongjun" sort="Wang, Yongjun" uniqKey="Wang Y" first="Yongjun" last="Wang">Yongjun Wang</name><name sortKey="Yoon, Byung Woo" sort="Yoon, Byung Woo" uniqKey="Yoon B" first="Byung-Woo" last="Yoon">Byung-Woo Yoon</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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HfdIndexSelect -h $EXPLOR_AREA/Data/Main/Exploration/RBID.i -Sk "pubmed:27507860" \
| HfdSelect -Kh $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd \
| NlmPubMed2Wicri -a AustralieFrV1
| This area was generated with Dilib version V0.6.33. |  |